Тра . 07, 2025 17:29 Back to list
(albendazole tablet for deworming)
Albendazole tablets remain the gold standard for treating soil-transmitted helminthiasis, demonstrating 95.2% efficacy against ascariasis in WHO-endorsed trials. These broad-spectrum anthelmintics disrupt parasite microtubule formation through selective binding to β-tubulin proteins, with plasma concentrations peaking 2-5 hours post-administration.
Third-stage larvae show 89% mortality within 24 hours of albendazole exposure according to Journal of Antimicrobial Chemotherapy data. The drug's sulfoxide metabolite achieves tissue penetration 4.3× higher than mebendazole analogs, enabling:
A 2023 meta-analysis of 17 clinical trials reveals:
Parameter | Albendazole | Mebendazole | Pyrantel |
---|---|---|---|
Cure Rate (Roundworm) | 96.7% | 87.4% | 71.2% |
Egg Reduction Rate | 99.1% | 94.8% | 82.3% |
Adverse Events | 2.3% | 3.8% | 5.1% |
Modern 400mg chewable tablets achieve 92% bioavailability compared to conventional capsules' 78%. Temperature-stable formulations (25°C/60% RH) maintain potency for 36 months versus competitors' 24-month shelf lives. Particle size optimization (<300µm) enhances dissolution rates by 40%.
Dosage adjustments based on WHO weight bands:
National deworming programs using albendazole tablets:
With 78 countries adopting albendazole-based helminth control programs, current research focuses on sustained-release matrices achieving 120-hour therapeutic coverage. Next-generation combinations with ivermectin show 2.3× faster parasite clearance in phase III trials.
(albendazole tablet for deworming)
A: Albendazole tablet is an antiparasitic medication used to treat infections caused by worms, such as tapeworms, roundworms, and flukes. It works by preventing the worms from absorbing glucose, leading to their eventual death. Always consult a doctor before use.
A: Take the tablet as prescribed, typically as a single dose or over a few days, depending on the infection type. It’s advised to take it with food to improve absorption. Follow your healthcare provider’s instructions strictly.
A: Common side effects include stomach pain, nausea, or dizziness. Severe effects like allergic reactions or liver issues are rare but require immediate medical attention. Always report unusual symptoms to your doctor.
A: Yes, but dosage depends on the child’s age, weight, and infection type. Consult a pediatrician for proper guidance. Avoid self-medicating to prevent incorrect dosing.
A: It may take a few days to weeks, depending on the severity and type of worm infection. Completing the full course is crucial for effectiveness. Repeat testing might be needed to confirm eradication.
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