The manifestations of Lumpy Skin Disease include the appearance of nodules on the skin, which can range from small lumps to large abscesses. These nodules can occur all over the body, including the head, neck, and limbs, potentially leading to pain, swelling, and secondary infections. In addition to skin lesions, infected animals may also exhibit fever, increased respiratory rate, and mucosal lesions. Some animals may suffer from weight loss and reduced milk production, which can have dire economic implications for farmers relying on these resources.