One of the most commonly found OTC anti-inflammatory options for dogs is non-steroidal anti-inflammatory drugs (NSAIDs). While some NSAIDs are specifically formulated for canine use (such as carprofen or meloxicam), there are also some human NSAIDs available OTC that may be considered. These include aspirin and ibuprofen, but great caution is needed as they can have significant side effects and are not always safe for dogs.