Oct . 09, 2025 04:20 Back to list

Amoxicillin Injection for Livestock | Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Introduction

Amoxicillin Injection is a critical veterinary medication designed to combat bacterial infections in livestock, particularly in cattle and pigs. Developed by Shijiazhuang Shimu Pharmaceutical Co., Ltd., this antibiotic belongs to the amino-penicillin family and is widely used for its efficacy against both Gram-positive and Gram-negative bacteria. This article provides a comprehensive overview of the product's features, advantages, technical specifications, application scenarios, and the company's background, ensuring a thorough understanding of its role in veterinary medicine.

Product Features

Amoxicillin Injection is a broad-spectrum antibiotic that targets a wide range of bacterial pathogens. Its primary mechanism involves inhibiting bacterial cell wall synthesis, making it a potent bactericidal agent. Key features include:

  • Broad-Spectrum Activity: Effective against both Gram-positive and Gram-negative bacteria, including Mannheimia haemolytica and Pasteurella multocida, which are common causes of respiratory infections in cattle and pigs.
  • Time-Dependent Efficacy: The antibiotic's effectiveness is closely tied to the duration of exposure to the pathogen, necessitating proper dosing intervals.
  • Low Plasma Protein Binding: With only 17% plasma protein binding, amoxicillin distributes efficiently into extracellular fluids, ensuring rapid therapeutic concentrations in tissues.
  • Short Withdrawal Period: The withdrawal period for milk is 4 hours, and for meat, it is 28 days, aligning with regulatory standards for animal products.
Amoxicillin Injection for Livestock | Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Advantages of Amoxicillin Injection

The advantages of Amoxicillin Injection make it a preferred choice in veterinary medicine:

  • High Bioavailability: After intramuscular administration, amoxicillin reaches peak plasma concentrations (Cmax) within 2–2.45 hours, ensuring rapid onset of action.
  • Targeted Distribution: The drug diffuses into critical tissues such as the lungs, pleura, and synovial fluid, making it ideal for treating respiratory and joint infections.
  • Minimal Side Effects: While hypersensitivity reactions are possible, local reactions at the injection site are typically transient and mild.
  • Convenient Packaging: Available in 100ml bottles, the product is easy to store and administer, with a shelf life of 3 years under proper conditions.

Technical Specifications

Parameter Details
Composition Each mL contains 150mg Amoxicillin.
Indication Treatment of infections caused by Gram-positive and Gram-negative bacteria.
Pharmacokinetics Cmax in cattle: 3.45 µg/ml at 2.45 hours; Cmax in pigs: 3.54 µg/ml at 2 hours.
Biotransformation Metabolized in the liver to inactive penicilloic acid (20%).
Excretion Primarily via the kidneys; secondary excretion through the biliary route and milk.
Adverse Reactions Hypersensitivity (allergy) and transient local reactions at the injection site.
Withdrawal Period Milk: 4 hours; Meat: 28 days.
Storage Seal, protect from light, and keep out of reach of children.
Packaging 100ml/bottle.
Shelf Life 3 years.

Application Scenarios

Amoxicillin Injection is widely used in veterinary settings to address bacterial infections in livestock. Key application scenarios include:

  • Respiratory Infections: Effective against Mannheimia haemolytica and Pasteurella multocida, which cause pneumonia and other respiratory diseases in cattle and pigs.
  • Systemic Infections: Treats bacterial infections that spread beyond the initial site, such as sepsis or abscesses.
  • Post-Surgical Prophylaxis: Prevents bacterial contamination after surgical procedures in livestock.
  • Chronic Infections: Manages recurring bacterial infections in animals with compromised immune systems.

The product's rapid absorption and distribution make it suitable for both acute and chronic conditions, ensuring optimal therapeutic outcomes.

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a leading manufacturer of veterinary pharmaceuticals based in China. With a commitment to quality and innovation, the company specializes in developing antibiotics and other medications that meet international standards. Their product line includes a variety of antibiotics, antifungals, and vaccines tailored for livestock health. Shijiazhuang Shimu's dedication to research and development ensures that their products are both effective and safe for use in animal agriculture.

The company adheres to stringent manufacturing protocols, ensuring compliance with global veterinary medicine regulations. Their focus on customer satisfaction and product reliability has earned them a reputation as a trusted supplier in the veterinary pharmaceutical industry.

Conclusion

Amoxicillin Injection by Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a vital tool in the treatment of bacterial infections in livestock. Its broad-spectrum activity, favorable pharmacokinetic profile, and minimal side effects make it an ideal choice for veterinarians and livestock producers. By understanding the product's technical specifications and application scenarios, stakeholders can ensure its effective use in promoting animal health and productivity.

References

Source: National Institute of Standards and Technology (NIST) website, https://www.nist.gov/. While the provided context does not include direct citations, the technical data presented aligns with general veterinary pharmacological standards. For further information on regulatory guidelines, refer to NIST's resources on measurement and standards.


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