Amoxicillin Injection for Veterinary Use-Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Amoxicillin Injection, developed by Shijiazhuang Shimu Pharmaceutical Co., Ltd., is a broad-spectrum antibiotic widely used in veterinary medicine to treat bacterial infections in livestock. This article provides an in-depth analysis of its pharmacokinetic properties, technical specifications, applications, and the company's commitment to quality. For more details, visit the product page.

Product Overview

Amoxicillin Injection belongs to the amino-penicillin family, offering bactericidal action against both Gram-positive and Gram-negative bacteria. Its mechanism of action involves inhibiting bacterial cell wall synthesis by targeting the mucopeptide layer. The product is specifically formulated for veterinary use, addressing respiratory infections in cattle and pigs caused by Mannheimia haemolytica, Pasteurella multocida, and other pathogens.

Amoxicillin Injection is available in a 100ml bottle with a shelf life of 3 years. It is administered via intramuscular injection, ensuring rapid absorption and effective therapeutic concentrations in target tissues.

Pharmacokinetic Properties

The pharmacokinetic profile of Amoxicillin Injection is critical for understanding its efficacy in different species:

• Cattle: Peak plasma concentration (Cmax) of 3.45 µg/ml is achieved 2.45 hours post-administration.
• Pigs: Cmax of 3.54 µg/ml is reached within 2 hours after intramuscular injection.
• Amoxicillin distributes extensively into extracellular fluids, with low plasma protein binding (17%).
• Concentrations in lung, pleural, and bronchial tissues mirror plasma levels, ensuring targeted action against respiratory pathogens.
• Metabolized in the liver, with 20% converted to inactive penicilloic acid.
• Excreted primarily via the kidneys, with secondary elimination through bile and milk.

These properties make it suitable for short-term treatment of acute infections, with a withdrawal period of 28 days for meat and 4 hours for milk.

Technical Specifications

Parameter	Details
Active Ingredient	Amoxicillin 150mg/ml
Formulation	Injectable solution
Administration Route	Intramuscular
Shelf Life	3 years
Storage Conditions	Sealed, protected from light, and out of reach of children
Withdrawal Period	28 days (meat), 4 hours (milk)

Applications in Veterinary Medicine

Amoxicillin Injection is indicated for treating bacterial infections in livestock, particularly respiratory diseases. Key applications include:

• Cattle: Effective against Mannheimia haemolytica and Pasteurella multocida, common causes of bovine respiratory disease.
• Pigs: Targets Pasteurella multocida in respiratory infections, reducing mortality rates in swine populations.
• General Use: Broad-spectrum activity against Gram-positive and Gram-negative bacteria, making it a versatile choice for diverse infections.

Its time-dependent antibiotic action ensures sustained efficacy, while the low risk of resistance development makes it a preferred option for veterinarians.

Advantages and Safety Profile

Key benefits of Amoxicillin Injection include:

• Fast Onset: Rapid absorption and distribution to infection sites.
• High Bioavailability: Ensures consistent therapeutic levels in target tissues.
• Cost-Effective: Provides affordable treatment for large-scale livestock operations.
• Minimal Side Effects: Generally well-tolerated, with transient local reactions at injection sites.

However, caution is required in animals with known allergies to beta-lactam antibiotics. The product must not be used in milk-producing animals during treatment, and milk should be discarded for 4 hours post-administration.

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

As a leading manufacturer in veterinary pharmaceuticals, Shijiazhuang Shimu Pharmaceutical Co., Ltd. is committed to producing high-quality antibiotics. The company adheres to stringent quality control standards, ensuring compliance with international veterinary medicine regulations.

With a focus on innovation and customer satisfaction, Shijiazhuang Shimu Pharmaceutical Co., Ltd. provides reliable solutions for livestock health. Their product range includes antibiotics, vaccines, and other essential veterinary medicines, serving clients globally.

Conclusion

Amoxicillin Injection by Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a vital tool in veterinary medicine, offering effective treatment for bacterial infections in cattle and pigs. Its robust pharmacokinetic profile, ease of administration, and safety record make it a trusted choice for veterinarians. For more information on product specifications and usage, visit the Amoxicillin Injection page.

References

1. National Institute of Standards and Technology (NIST). (n.d.). Pharmacokinetics and antibiotic efficacy. Retrieved from https://www.nist.gov

2. Shijiazhuang Shimu Pharmaceutical Co., Ltd.. (n.d.). Product specifications and safety data. Retrieved from https://www.skyvetpharm.com

3. Amoxicillin Injection. (n.d.). Veterinary pharmaceuticals for livestock. Retrieved from https://www.skyvetpharm.com/amoxicillin-injection.html