Amoxicillin Injection - Shijiazhuang Shimu Pharmaceutical Co., Ltd.|Broad-Spectrum Antibiotic&Veterinary Use

Introduction to Amoxicillin Injection

Amoxicillin Injection is a critical pharmaceutical product designed for the treatment of bacterial infections in veterinary medicine. As a member of the amino-penicillin family, it offers broad-spectrum activity against both Gram-positive and Gram-negative bacteria. This article provides an in-depth analysis of its pharmacokinetic properties, advantages, technical specifications, and applications, alongside insights into the company behind the product, Shijiazhuang Shimu Pharmaceutical Co., Ltd..

Pharmacokinetic Properties

Amoxicillin Injection is a bactericidal antibiotic that inhibits bacterial cell wall synthesis by targeting the mucopeptide layer. Its efficacy against pathogens like Mannheimia haemolytica and Pasteurella multocida makes it a preferred choice for respiratory infections in cattle and pigs. The drug's pharmacokinetic profile ensures rapid absorption and distribution, as detailed below:

Key Pharmacokinetic Data

• Cmax (Maximum Concentration): In cattle, Cmax reaches 3.45 µg/ml within 2.45 hours after intramuscular administration. In pigs, it achieves 3.54 µg/ml in 2 hours.
• Distribution: Amoxicillin is primarily distributed in the extracellular compartment, with minimal plasma protein binding (17%). It effectively penetrates tissues such as pulmonary, pleural, and bronchial tissues, matching plasma concentrations.
• Metabolism: The drug is biotransformed in the liver via hydrolysis of the β-lactam ring, producing inactive penicilloic acid (20% of the original compound).
• Excretion: Amoxicillin is predominantly excreted via the kidneys, with secondary routes including the biliary system and milk.

These properties ensure sustained therapeutic levels in target tissues, making it effective for treating infections in livestock.

Advantages of Amoxicillin Injection

Amoxicillin Injection offers several advantages that make it a trusted solution in veterinary medicine:

• Broad-Spectrum Activity: Effective against a wide range of bacteria, including those causing respiratory and systemic infections.
• Fast Onset of Action: Rapid absorption and distribution ensure quick therapeutic effects.
• High Bioavailability: Intramuscular administration ensures reliable drug delivery.
• Cost-Effective: Provides an affordable treatment option for large-scale livestock operations.

Additionally, its safety profile, when used as directed, minimizes the risk of adverse effects, making it a preferred choice for veterinarians.

Technical Specifications

Below is a detailed table outlining the technical specifications of Amoxicillin Injection:

Applications in Veterinary Medicine

Amoxicillin Injection is widely used in the treatment of bacterial infections in livestock, particularly in the following scenarios:

• Respiratory Infections: Effective against Mannheimia haemolytica and Pasteurella multocida in cattle and pigs.
• Systemic Infections: Treats bacterial infections affecting multiple organs or systems.
• Post-Surgical Prophylaxis: Prevents infections following surgical procedures in animals.
• Chronic Infections: Provides long-term management of recurrent bacterial infections.

The drug's ability to penetrate tissues and maintain therapeutic concentrations makes it ideal for these applications. For more details on its uses, visit Amoxicillin Injection Uses.

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a leading manufacturer of veterinary pharmaceuticals, dedicated to providing high-quality solutions for livestock health. With a focus on innovation and compliance, the company ensures that its products meet stringent safety and efficacy standards. Their commitment to research and development has established them as a trusted name in the veterinary industry.

For more information about the company, visit their official website Shijiazhuang Shimu Pharmaceutical Co., Ltd..

Important Safety and Usage Guidelines

To ensure the safe and effective use of Amoxicillin Injection, the following precautions must be observed:

• Allergies: Do not use in animals with a known allergy to β-lactam antibiotics.
• Administration: Shake the vial well before use to ensure proper mixing.
• Milk Withdrawal: Avoid using milk from treated animals for human consumption during the withdrawal period.
• Storage: Store in a cool, dry place away from direct sunlight.

Adhering to these guidelines minimizes the risk of adverse effects and ensures compliance with regulatory standards.

Conclusion

Amoxicillin Injection is a vital tool in the fight against bacterial infections in livestock, offering a combination of efficacy, safety, and cost-effectiveness. Its robust pharmacokinetic profile, broad-spectrum activity, and ease of administration make it a preferred choice for veterinarians worldwide. As a product of Shijiazhuang Shimu Pharmaceutical Co., Ltd., it reflects the company's commitment to innovation and quality in veterinary healthcare.

For further details, explore the Amoxicillin Injection page or contact the company directly.

References

1. National Institute of Standards and Technology (NIST). (2025). Standards and Measurements. Retrieved from https://www.nist.gov.

2. Shijiazhuang Shimu Pharmaceutical Co., Ltd. (2025). Amoxicillin Injection Specifications. Retrieved from https://www.skyvetpharm.com.