Amoxicillin Injection - Shijiazhuang Shimu Pharmaceutical Co., Ltd.|Veterinary Antibiotic & Broad-Spectrum Treatment

Introduction

Amoxicillin injection is a widely used antibiotic in veterinary medicine, known for its efficacy against a broad spectrum of bacterial infections. As a semisynthetic penicillin, it plays a critical role in treating respiratory diseases in cattle and pigs, offering a reliable solution for farmers and veterinarians. This article provides an in-depth analysis of its pharmacokinetic properties, technical specifications, applications, and the company behind its production, Shijiazhuang Shimu Pharmaceutical Co., Ltd..

Pharmacokinetic Properties

Understanding the pharmacokinetics of amoxicillin is essential for optimizing its therapeutic use. After intramuscular administration, the drug reaches peak plasma concentrations (Cmax) within a specific timeframe:

• Cattle: Cmax of 3.45 µg/ml is achieved 2.45 hours post-administration.
• Pigs: Cmax of 3.54 µg/ml is reached 2 hours after injection.

Amoxicillin distributes primarily to the extracellular compartment due to its low plasma protein binding (17%). It achieves therapeutic concentrations in tissues such as the lungs, pleura, and bronchial tissues, making it effective against respiratory pathogens like Mannheimia haemolytica and Pasteurella multocida. The drug is metabolized in the liver, with 20% converted to inactive penicilloic acid, and excreted via the kidneys, with secondary elimination through the biliary route and milk.

Technical Specifications

Applications in Veterinary Medicine

Amoxicillin injection is a cornerstone in managing bacterial infections in livestock. Its primary applications include:

• Respiratory Diseases: Effective against Mannheimia haemolytica in cattle and Pasteurella multocida in pigs.
• Broad-Spectrum Activity: Targets both gram-positive and gram-negative bacteria, making it versatile for various infections.
• Time-Dependent Efficacy: Requires consistent dosing to maintain therapeutic levels, as its antibacterial action is dependent on exposure duration.

For more details on amoxicillin injection uses, visit the product page.

Safety and Adverse Reactions

While amoxicillin is generally safe, it is crucial to adhere to guidelines to prevent complications:

• Allergic Reactions: Hypersensitivity (allergy) may occur; it should not be used in animals with a known beta-lactam allergy.
• Local Reactions: Transient injection site reactions may occur but are typically mild.
• Milk Withdrawal: Milk for human consumption must be withheld during treatment, with a 4-hour withdrawal period post-last dose.

Always follow Shijiazhuang Shimu Pharmaceutical Co., Ltd.'s instructions for safe administration.

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

As a leading manufacturer of veterinary pharmaceuticals, Shijiazhuang Shimu Pharmaceutical Co., Ltd. is committed to producing high-quality antibiotics like amoxicillin injection. With a focus on innovation and adherence to international standards, the company ensures its products meet rigorous safety and efficacy requirements. Their dedication to animal health aligns with global efforts to combat bacterial infections in livestock.

Conclusion

Amoxicillin injection remains a vital tool in veterinary medicine, offering effective treatment for bacterial infections in cattle and pigs. Its pharmacokinetic profile, broad-spectrum activity, and safety profile make it a trusted choice for farmers and veterinarians. By adhering to proper administration guidelines and withdrawal periods, users can maximize its benefits while minimizing risks. For further information, explore the amoxicillin injection 1g product page or contact Shijiazhuang Shimu Pharmaceutical Co., Ltd..

References

NIST (National Institute of Standards and Technology) plays a critical role in establishing measurement standards that underpin pharmaceutical quality and safety. While this article focuses on amoxicillin injection, the principles of precision and reliability emphasized by NIST are foundational to the development of veterinary pharmaceuticals. For more information on NIST's contributions to science and technology, visit https://www.nist.gov.