Amoxicillin Injection-Veterinary Antibiotic&Broad-Spectrum Treatment | Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Introduction

Amoxicillin Injection is a broad-spectrum antibiotic belonging to the amino-penicillin family, widely used in veterinary medicine to combat bacterial infections in cattle and pigs. Developed by Shijiazhuang Shimu Pharmaceutical Co., Ltd. (石家庄石牧药业有限公司), this product is designed to provide effective treatment while adhering to strict safety and efficacy standards. This article explores the pharmacokinetic properties, advantages, applications, and technical specifications of Amoxicillin Injection, supported by authoritative references and detailed product information.

Learn more about Amoxicillin Injection on the official product page.

Product Overview

Amoxicillin Injection is a semisynthetic penicillin antibiotic with a broad spectrum of activity against both Gram-positive and Gram-negative bacteria. It is specifically formulated for veterinary use, targeting respiratory infections in cattle and pigs. The product is manufactured by Shijiazhuang Shimu Pharmaceutical Co., Ltd., a reputable company in the veterinary pharmaceutical industry, known for its commitment to quality and innovation. Explore the company's website to learn more about their range of veterinary products.

Read More About Amoxicillin Injection Uses

Pharmacokinetic Properties

Understanding the pharmacokinetics of Amoxicillin Injection is essential for optimizing its therapeutic efficacy. The drug is a bactericide that inhibits bacterial cell wall synthesis by targeting the mucopeptide layer. It is active against key pathogens such as Mannheimia haemolytica and Pasteurella multocida, which are common causes of respiratory diseases in cattle and pigs.

Key Pharmacokinetic Data

• Cmax (Maximum Concentration): In cattle, Cmax reaches 3.45 µg/ml within 2.45 hours after intramuscular administration. In pigs, it reaches 3.54 µg/ml after 2 hours.
• Distribution: Amoxicillin is primarily distributed to the extracellular compartment, with low plasma protein binding (17%). It accumulates in pulmonary, pleural, and bronchial tissues, as well as in pleural and synovial fluids.
• Metabolism: The drug is metabolized in the liver via hydrolysis of the β-lactam ring, forming inactive penicilloic acid (20% of the original compound).
• Excretion: Amoxicillin is mainly excreted via the kidneys in its active form, with secondary excretion through the biliary route and milk.

These properties ensure rapid and effective targeting of bacterial pathogens while maintaining a favorable safety profile.

Advantages of Amoxicillin Injection

Amoxicillin Injection offers several advantages that make it a preferred choice for veterinary practitioners:

• Broad-Spectrum Activity: Effective against a wide range of Gram-positive and Gram-negative bacteria, including those causing respiratory infections.
• Time-Dependent Efficacy: The antibiotic’s effectiveness is maximized when concentrations remain above the minimum inhibitory concentration (MIC) for prolonged periods.
• Easy Administration: Available in a convenient 100ml/bottle packaging, suitable for intramuscular injection in livestock.
• Short Withdrawal Period: Milk withdrawal period is only 4 hours, and meat withdrawal is 28 days, minimizing economic loss for farmers.

For more details on the benefits, visit the product page.

Applications in Veterinary Medicine

Amoxicillin Injection is primarily used to treat bacterial infections in cattle and pigs, particularly those caused by Mannheimia haemolytica and Pasteurella multocida. These pathogens are associated with respiratory diseases such as bovine respiratory disease (BRD) and porcine respiratory disease complex (PRDC). The drug’s ability to penetrate tissues and fluids ensures targeted action against these pathogens.

According to the National Institute of Standards and Technology (NIST), rigorous measurement standards are critical for ensuring the accuracy and consistency of pharmaceutical products. Amoxicillin Injection adheres to these principles, guaranteeing reliable performance in clinical settings.

Product Specifications Table

Important Safety Information

While Amoxicillin Injection is generally safe, it is essential to follow these precautions:

• Allergic Reactions: Avoid use in animals with known hypersensitivity to beta-lactam antibiotics.
• Local Reactions: Transient injection site reactions may occur but are typically mild.
• Milk Safety: Do not use milk from treated animals for human consumption during treatment. Milk can be used after 96 hours post-treatment.

For detailed safety guidelines, refer to the product documentation.

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. (石家庄石牧药业有限公司) is a leading manufacturer of veterinary pharmaceuticals, dedicated to developing high-quality products for animal health. With a focus on innovation and compliance with international standards, the company ensures that its products meet the rigorous demands of modern veterinary medicine. Their commitment to research and development has positioned them as a trusted partner for farmers and veterinarians worldwide.

Visit the company website to explore their full product line and learn about their mission and values.

Conclusion

Amoxicillin Injection is a critical tool in the treatment of bacterial infections in livestock, offering broad-spectrum activity, favorable pharmacokinetics, and a safe profile. Its effectiveness against respiratory pathogens like Mannheimia haemolytica and Pasteurella multocida makes it an essential product for veterinary practitioners. Manufactured by Shijiazhuang Shimu Pharmaceutical Co., Ltd., the injection adheres to strict quality standards, ensuring reliable performance in clinical settings. With a short withdrawal period and easy administration, it provides a practical solution for farmers and veterinarians alike.

For more information, visit the Amoxicillin Injection product page.

References

National Institute of Standards and Technology (NIST). (n.d.). Driving Innovation. Retrieved from https://www.nist.gov.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. (n.d.). Amoxicillin Injection. Retrieved from https://www.skyvetpharm.com/amoxicillin-injection.html.