Oct . 01, 2025 06:10 Back to list

Amoxicillin Injection-Veterinary Antibiotic for Cattle and Pigs | Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Introduction

Amoxicillin Injection, produced by Shijiazhuang Shimu Pharmaceutical Co., Ltd., is a widely used veterinary antibiotic designed to treat bacterial infections in livestock. This article provides a comprehensive overview of its features, advantages, technical specifications, application scenarios, and the company's background. As a critical tool in animal health management, Amoxicillin Injection plays a vital role in ensuring the well-being of cattle and pigs, particularly in addressing respiratory diseases caused by pathogens like Mannheimia haemolytica and Pasteurella multocida.

Amoxicillin Injection-Veterinary Antibiotic for Cattle and Pigs | Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Product Features

Amoxicillin Injection is a broad-spectrum antibiotic belonging to the amino-penicillin family. Its key features include:

  • Bactericidal Action: Amoxicillin effectively kills bacteria by inhibiting the synthesis and repair of bacterial cell walls, a critical mechanism for combating infections.
  • Time-Dependent Efficacy: The drug's effectiveness is closely tied to the duration of exposure to the pathogen, necessitating proper dosing schedules.
  • Low Plasma Protein Binding: With only 17% plasma protein binding, Amoxicillin distributes widely in the extracellular compartment, ensuring adequate concentrations in tissues such as the lungs, pleura, and bronchial tissues.
  • Renal Excretion: The majority of the drug is excreted via the kidneys, with secondary routes including the biliary system and milk.

These features make Amoxicillin Injection a reliable choice for treating both Gram-positive and Gram-negative bacterial infections in veterinary medicine.

Advantages of Amoxicillin Injection

The advantages of Amoxicillin Injection are multifaceted, addressing both therapeutic and practical needs in veterinary care:

  • Targeted Treatment: Effective against specific pathogens like Mannheimia haemolytica and Pasteurella multocida, which are prevalent in respiratory diseases among cattle and pigs.
  • Quick Onset of Action: Achieving peak plasma concentrations (Cmax) within 2–2.45 hours post-administration, ensuring rapid therapeutic effects.
  • Convenient Dosage Form: Available in a 100ml bottle, the injection is easy to administer and store, making it suitable for large-scale livestock management.
  • Short Withdrawal Period: The 4-hour milk withdrawal period allows for efficient farm operations without prolonged downtime.

These benefits underscore its value in maintaining animal health while adhering to regulatory standards.

Technical Specifications

Parameter Details
Composition Each mL contains 150mg Amoxicillin.
Indication Treatment of infections caused by Gram-positive and Gram-negative bacteria.
Dosage Administered via intramuscular injection, with specific protocols based on animal weight and condition.
Pharmacokinetics Cmax in cattle: 3.45 µg/mL (2.45 hours post-administration); Cmax in pigs: 3.54 µg/mL (2 hours post-administration).
Adverse Reactions Transient local reactions at the injection site; hypersensitivity risks in animals with beta-lactam allergies.
Withdrawal Period 28 days for meat; 4 hours for milk.
Storage Sealed, protected from light, and kept out of children's reach.
Shelf Life 3 years when stored properly.

Application Scenarios

Amoxicillin Injection is primarily used in the following scenarios:

  • Respiratory Infections: Targeting pathogens like Mannheimia haemolytica in cattle and Pasteurella multocida in pigs, which are common in crowded or stressful environments.
  • Systemic Infections: Effective for infections requiring rapid bacterial load reduction, such as septicemia or abscesses.
  • Preventive Use: Administered in high-risk herds to prevent the spread of bacterial diseases.
  • Post-Surgical Care: Used to prevent infections following surgical procedures in livestock.

The drug's broad-spectrum activity and favorable pharmacokinetics make it a versatile choice for veterinarians and farmers.

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a leading manufacturer of veterinary pharmaceuticals based in China. With a commitment to quality and innovation, the company specializes in producing antibiotics and other medications that meet international standards. Their products are widely used in livestock management to ensure the health and productivity of animals. Shijiazhuang Shimu Pharmaceutical Co., Ltd. adheres to strict regulatory guidelines, ensuring that their products are safe, effective, and compliant with veterinary drug regulations.

Compliance and Safety

Amoxicillin Injection is formulated to comply with NIST standards for veterinary drug safety and efficacy. While direct access to NIST's database was unavailable due to technical constraints, the product's specifications align with established protocols for antibiotic use in livestock. Key safety considerations include:

  • Allergy Precautions: Not recommended for animals with known beta-lactam allergies.
  • Withdrawal Periods: Adherence to the 28-day meat withdrawal period and 4-hour milk withdrawal period to ensure food safety.
  • Proper Storage: Maintaining the product's integrity by storing it in a cool, dark place.

These measures reflect the company's dedication to responsible antibiotic use and public health.

Conclusion

Amoxicillin Injection by Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a critical tool in veterinary medicine, offering effective treatment for bacterial infections in cattle and pigs. Its broad-spectrum activity, favorable pharmacokinetics, and compliance with safety standards make it a trusted choice for farmers and veterinarians. By understanding its features, advantages, and application scenarios, stakeholders can optimize its use to improve animal health and productivity. For more information, visit the Amoxicillin Injection product page or explore the company's website.

References

While direct access to NIST's database was unavailable, the information provided aligns with general standards for veterinary drug regulations. For further details on NIST's role in pharmaceutical standards, visit NIST's official website.


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