Amoxicillin Injection-Veterinary Antibiotic|Cattle & Pigs Treatment

Amoxicillin Injection is a critical pharmaceutical solution designed for the treatment of bacterial infections in livestock, particularly cattle and pigs. Manufactured by Shijiazhuang Shimu Pharmaceutical Co., Ltd., this product combines advanced pharmacological properties with rigorous quality standards to ensure efficacy and safety. This article explores the core features, technical specifications, application scenarios, and company background of this essential veterinary medication.

Product Overview

Amoxicillin Injection belongs to the amino-penicillin family, a class of broad-spectrum antibiotics known for their ability to combat both Gram-positive and Gram-negative bacteria. Its mechanism of action involves inhibiting bacterial cell wall synthesis, making it a potent bactericidal agent. This product is specifically formulated for veterinary use, addressing respiratory infections caused by pathogens such as Mannheimia haemolytica and Pasteurella multocida in cattle and pigs.

Manufactured by Shijiazhuang Shimu Pharmaceutical Co., Ltd., a reputable pharmaceutical company based in China, Amoxicillin Injection adheres to strict quality control protocols. The company’s commitment to innovation and compliance with international standards ensures that the product meets the highest levels of safety and effectiveness.

Pharmacokinetic Properties

Amoxicillin Injection exhibits favorable pharmacokinetic characteristics, making it an ideal choice for veterinary applications. Upon intramuscular administration, the drug reaches peak plasma concentrations (Cmax) within 2–2.45 hours in cattle and pigs. Its low plasma protein binding (17%) allows for widespread distribution in extracellular compartments, including pulmonary, pleural, and bronchial tissues. This distribution pattern ensures effective targeting of respiratory pathogens in livestock.

The drug is primarily metabolized in the liver through hydrolysis of the β-lactam ring, resulting in the formation of inactive penicilloic acid. Approximately 20% of the drug is converted into this metabolite. Amoxicillin is predominantly excreted via the kidneys, with secondary excretion through the biliary route and milk. These properties contribute to its prolonged therapeutic effect and minimal systemic toxicity.

Technical Specifications

Feature	Description
Active Ingredient	Amoxicillin (150 mg/ml)
Formulation	Injectable Solution
Administration Route	Intramuscular
Pharmacokinetic Profile	Cmax: 3.45 µg/ml (cattle), 3.54 µg/ml (pigs); T1/2: 1.5–2 hours
Withdrawal Period	Cattle and Pigs: 28 days; Milk: 4 hours
Storage	Sealed, protected from light, and kept out of reach of children
Packaging	100 ml/bottle
Shelf Life	3 years

Application Scenarios

Amoxicillin Injection is widely used in veterinary medicine to treat bacterial infections in cattle and pigs. Its efficacy against Mannheimia haemolytica and Pasteurella multocida makes it a preferred choice for managing respiratory diseases such as bovine respiratory disease (BRD) and swine pneumonia. These infections are common in intensive farming systems, where close animal contact and stress factors increase the risk of bacterial outbreaks.

The product’s rapid onset of action and sustained therapeutic effect make it suitable for both acute and chronic infections. Veterinarians often recommend Amoxicillin Injection for its ability to penetrate deep into tissues, including pleural and synovial fluids, ensuring comprehensive bacterial eradication. Additionally, its low toxicity profile minimizes the risk of adverse reactions, making it a safe option for livestock treatment.

Adverse Reactions and Precautions

As with all penicillins, Amoxicillin Injection may cause hypersensitivity reactions in animals with known allergies to β-lactam antibiotics. While rare, transient local reactions at the injection site may occur. To mitigate these risks, it is crucial to follow the recommended dosage and administration guidelines.

Special Warnings include shaking the solution well before use and avoiding milk consumption during treatment. Milk from treated cattle must not be used for human consumption for 96 hours post-treatment. These precautions ensure the safety of both animals and consumers while maintaining the drug’s therapeutic efficacy.

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a leading pharmaceutical company specializing in veterinary medicine. With a focus on innovation and quality, the company develops and distributes a wide range of antibiotics, vaccines, and other veterinary products. Its commitment to scientific research and adherence to international standards has earned it a reputation as a trusted supplier in the global veterinary market.

Based in Hebei Province, China, the company leverages advanced manufacturing technologies and rigorous quality control systems to ensure the safety and efficacy of its products. Shijiazhuang Shimu Pharmaceutical Co., Ltd. also prioritizes sustainability and ethical practices, aligning its operations with global environmental and health regulations.

Why Choose Amoxicillin Injection?

Amoxicillin Injection offers several advantages over alternative antibiotics, including its broad-spectrum activity, favorable pharmacokinetic profile, and cost-effectiveness. Its ability to target multiple bacterial species makes it a versatile treatment option for livestock farmers. Additionally, the product’s long shelf life and easy storage requirements reduce logistical challenges for veterinary practitioners.

For farmers and veterinarians, Amoxicillin Injection provides a reliable solution to combat bacterial infections while minimizing the risk of drug resistance. Its compliance with withdrawal period guidelines ensures that treated animals can be safely reintegrated into the food supply chain, maintaining consumer confidence in meat and dairy products.

References and Authoritative Citations

While specific NIST standards for Amoxicillin Injection could not be directly retrieved due to technical limitations, the National Institute of Standards and Technology (NIST) plays a critical role in establishing pharmaceutical standards. According to NIST’s official website, the organization develops measurement standards and testing protocols to ensure the accuracy and reliability of medical products. These standards are essential for verifying the quality and efficacy of antibiotics like amoxicillin.

For further information on NIST’s contributions to pharmaceutical science, visit NIST’s official website.

Conclusion

Amoxicillin Injection by Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a vital tool in veterinary medicine, offering effective treatment for bacterial infections in cattle and pigs. Its robust pharmacological properties, combined with the company’s commitment to quality, make it a trusted choice for livestock health management. By adhering to strict safety protocols and withdrawal periods, this product ensures the well-being of animals and the integrity of the food supply chain.

For more details about Amoxicillin Injection, visit the product page or explore the company website to learn more about Shijiazhuang Shimu Pharmaceutical Co., Ltd..