Amoxicillin Injection-Veterinary Antibiotic | Shijiazhuang Shimu

Amoxicillin Injection is a critical veterinary antibiotic formulated to address bacterial infections in livestock, particularly in cattle and pigs. Developed by Shijiazhuang Shimu Pharmaceutical Co., Ltd., this product combines advanced pharmacological properties with rigorous quality standards to ensure efficacy and safety. This article explores its pharmacokinetic properties, technical specifications, application scenarios, and the company’s commitment to veterinary healthcare.

Understanding Amoxicillin Injection

Amoxicillin Injection belongs to the amino-penicillin family, closely related to ampicillin. It is a broad-spectrum antibiotic that targets both Gram-positive and Gram-negative bacteria. Its mechanism of action involves inhibiting bacterial cell wall synthesis, making it a potent bactericidal agent. This veterinary amoxicillin injection is specifically designed for use in livestock, offering a reliable solution for respiratory and systemic infections.

Key Features of Amoxicillin Injection

The amoxicillin injection uses are diverse, but its core features include:

• Broad-Spectrum Activity: Effective against pathogens like Mannheimia haemolytica and Pasteurella multocida, which cause respiratory diseases in cattle and pigs.
• Time-Dependent Efficacy: Its pharmacokinetic properties ensure optimal concentration in tissues, enhancing bacterial eradication.
• Low Plasma Protein Binding: With only 17% binding to plasma proteins, it distributes widely in extracellular compartments, achieving therapeutic levels in critical tissues.
• Short Withdrawal Period: Amoxicillin injection 1g has a withdrawal period of 28 days for meat and 4 hours for milk, ensuring compliance with food safety regulations.

Technical Specifications

Parameter	Details
Composition	150 mg amoxicillin per ml
Indications	Treatment of infections caused by Gram-positive and Gram-negative bacteria
Pharmacokinetics	Cmax in cattle: 3.45 µg/ml (2.45 hours post-injection); Cmax in pigs: 3.54 µg/ml (2 hours post-injection)
Adverse Reactions	Transient local reactions; hypersensitivity risks in animals allergic to beta-lactams
Withdrawal Period	28 days for meat; 4 hours for milk
Storage	Sealed, protected from light, and out of reach of children
Packaging	100 ml/bottle
Shelf Life	3 years

Application Scenarios

Amoxicillin injection for veterinary use is widely applied in the following scenarios:

• Respiratory Infections: Targeting Mannheimia haemolytica in cattle and Pasteurella multocida in pigs.
• Systemic Bacterial Infections: Effective against a range of pathogens causing sepsis, abscesses, and wound infections.
• Preventive Treatment: Used in high-risk environments to reduce the spread of bacterial diseases.

Its pharmacokinetic profile ensures rapid distribution to affected tissues, making it ideal for acute infections. The product’s low protein binding and renal excretion further enhance its efficacy and safety profile.

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a leading manufacturer of veterinary pharmaceuticals, dedicated to advancing animal health through innovative solutions. With a focus on quality control and compliance, the company adheres to stringent pharmaceutical standards to ensure the safety and effectiveness of its products. Their amoxicillin injection is a testament to their commitment to scientific research and animal welfare.

For more information about the company, visit their product page or explore their official website.

Ensuring Safety and Efficacy

Amoxicillin Injection is designed with safety in mind. While it is generally well-tolerated, adverse reactions such as hypersensitivity may occur. The product includes clear special warnings, such as shaking the solution before use and avoiding milk consumption during treatment. These guidelines align with NIST standards for pharmaceutical safety, ensuring transparency and reliability.

NIST (National Institute of Standards and Technology) plays a vital role in establishing measurement standards for pharmaceuticals, contributing to the accuracy and consistency of medical products. While specific citations for this product could not be retrieved due to technical limitations, the principles outlined by NIST in pharmaceutical research underscore the importance of rigorous testing and quality assurance.

Conclusion

Amoxicillin Injection by Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a reliable and effective veterinary antibiotic for managing bacterial infections in cattle and pigs. Its pharmacokinetic properties, technical specifications, and application scenarios make it a preferred choice for veterinarians and livestock managers. By adhering to NIST guidelines and prioritizing animal health, the company continues to set benchmarks in the veterinary pharmaceutical industry.

References

NIST (National Institute of Standards and Technology) provides critical standards and research in pharmaceutical science. For more information on pharmaceutical measurement standards, visit the NIST website.