Amoxicillin Injection-Veterinary Use|Broad-Spectrum Antibiotic&Effective Treatment

Amoxicillin Injection, a critical component in veterinary medicine, is a broad-spectrum antibiotic derived from the amino-penicillin family. This article delves into the pharmacokinetic properties, advantages, technical specifications, and applications of Amoxicillin Injection, while also highlighting the reputable background of its manufacturer, Shijiazhuang Shimu Pharmaceutical Co., Ltd.. For those seeking detailed insights into its use, Read More About amoxicillin injection uses.

Understanding Amoxicillin Injection

Amoxicillin Injection is a semisynthetic penicillin antibiotic designed to combat a wide range of bacterial infections in livestock. Its mechanism of action involves inhibiting the synthesis and repair of bacterial cell walls, making it effective against both Gram-positive and Gram-negative bacteria. This medication is particularly valued for its efficacy in treating respiratory diseases in cattle and pigs, such as those caused by Mannheimia haemolytica and Pasteurella multocida. Amoxicillin injection uses extend beyond respiratory infections, addressing various bacterial conditions in veterinary settings.

Pharmacokinetic Properties

Understanding the pharmacokinetics of Amoxicillin Injection is essential for its optimal use. After intramuscular administration, the drug reaches peak plasma concentrations (Cmax) within specific timeframes: 2.45 hours in cattle and 2 hours in pigs. Its low plasma protein binding (17%) facilitates widespread distribution, including into pulmonary, pleural, and bronchial tissues. Amoxicillin is primarily excreted via the kidneys, with secondary excretion through the biliary route and milk. These properties ensure effective therapeutic levels in target tissues while minimizing systemic toxicity.

Advantages of Amoxicillin Injection

Amoxicillin Injection offers several advantages that make it a preferred choice in veterinary medicine:

• Broad-Spectrum Activity: Effective against both Gram-positive and Gram-negative bacteria, including pathogens responsible for respiratory infections in livestock.
• Time-Dependent Efficacy: Its bactericidal action is enhanced by prolonged exposure to the drug, ensuring sustained therapeutic effects.
• Minimal Side Effects: While hypersensitivity reactions are possible, adverse effects are generally transient and localized to the injection site.
• Regulatory Compliance: Manufactured under strict quality standards, ensuring safety and efficacy for both animals and humans.

Technical Specifications

Parameter	Details
Composition	Each ml contains Amoxicillin 150mg.
Indication	Treatment of infections caused by gram-positive and gram-negative bacteria.
Withdrawal Period	Cattle and pigs: 28 days; Milk: 4 hours.
Storage	Seal and protect from light. Keep out of reach of children.
Packaging	100ml/bottle.
Shelf Life	3 years.

Applications in Veterinary Medicine

Amoxicillin Injection is widely used in veterinary practice for treating bacterial infections in cattle and pigs. Its efficacy against Mannheimia haemolytica and Pasteurella multocida makes it a cornerstone in managing respiratory diseases. Additionally, its ability to achieve therapeutic concentrations in tissues and fluids ensures broad coverage against various pathogens. Veterinary amoxicillin injection is also employed in post-operative care and as a prophylactic measure in high-risk environments.

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a reputable manufacturer of veterinary pharmaceuticals, committed to producing high-quality antibiotics like Amoxicillin Injection. With a focus on innovation and compliance with international standards, the company ensures that its products meet rigorous safety and efficacy criteria. Their dedication to research and development aligns with the principles of NIST (National Institute of Standards and Technology), which emphasizes precision and reliability in measurement and standards. This commitment to quality is reflected in the consistent performance of Amoxicillin Injection in clinical settings.

Important Considerations and Safety

While Amoxicillin Injection is generally safe, certain precautions must be observed:

• Allergy Risk: It should not be administered to animals with a known hypersensitivity to beta-lactams.
• Withdrawal Periods: Adherence to the specified withdrawal periods (28 days for cattle/pigs and 4 hours for milk) is crucial to ensure food safety.
• Storage: Proper storage conditions (protected from light and out of reach of children) are essential to maintain potency.

Conclusion

Amoxicillin Injection stands as a vital tool in veterinary medicine, offering effective treatment for bacterial infections in livestock. Its broad-spectrum activity, favorable pharmacokinetic profile, and adherence to stringent quality standards make it a reliable choice for veterinarians. As highlighted by NIST's emphasis on precision and measurement, the development and use of such antibiotics underscore the importance of scientific rigor in pharmaceutical production. For more information on amoxicillin injection uses and the company's commitment to quality, visit Shijiazhuang Shimu Pharmaceutical Co., Ltd..

References

NIST (National Institute of Standards and Technology): https://www.nist.gov/

Shijiazhuang Shimu Pharmaceutical Co., Ltd. https://www.skyvetpharm.com