Amoxicillin Injection-Veterinary Use|Cattle Pig Treatment

Amoxicillin Injection is a broad-spectrum antibiotic widely used in veterinary medicine to treat bacterial infections in livestock. Developed by Shijiazhuang Shimu Pharmaceutical Co., Ltd., this product is specifically formulated for use in cattle and pigs, addressing common respiratory pathogens. Its efficacy, safety profile, and compliance with regulatory standards make it a trusted choice among veterinarians and livestock producers.

Key Features of Amoxicillin Injection

Amoxicillin Injection belongs to the amino-penicillin family, closely related to ampicillin. It acts as a bactericidal agent, targeting both Gram-positive and Gram-negative bacteria by inhibiting the synthesis and repair of bacterial cell walls. This mechanism of action ensures rapid and effective treatment of infections caused by susceptible microorganisms.

The product’s pharmacokinetic properties are optimized for veterinary applications. After intramuscular administration, it reaches peak plasma concentrations (Cmax) within 2–2.45 hours in cattle and 2 hours in pigs. Its low plasma protein binding (17%) allows for wide distribution into extracellular compartments, including pulmonary, pleural, and bronchial tissues. This ensures therapeutic concentrations in critical areas affected by respiratory diseases.

Amoxicillin Injection is primarily excreted via the kidneys, with a secondary route through the biliary system and milk. This excretion profile necessitates careful management of withdrawal periods to ensure food safety. The product is available in a 100ml bottle, with a shelf life of 3 years when stored properly.

Advantages of Amoxicillin Injection

One of the primary advantages of Amoxicillin Injection is its broad-spectrum activity against common pathogens in livestock. It is particularly effective against Mannheimia haemolytica and Pasteurella multocida, which are major causes of respiratory infections in cattle and pigs. This makes it a versatile solution for managing outbreaks in agricultural settings.

The product’s time-dependent antibiotic nature ensures that consistent plasma concentrations are maintained for optimal bacterial suppression. Unlike concentration-dependent antibiotics, which require high doses, Amoxicillin Injection achieves therapeutic effects through sustained exposure, reducing the risk of resistance development.

Additionally, Amoxicillin Injection is formulated for ease of use. Its ready-to-administer solution requires minimal preparation, making it suitable for on-farm application. The product’s stability under standard storage conditions (protected from light and out of reach of children) further enhances its practicality for veterinary professionals.

Technical Specifications Table

Parameter	Details
Active Ingredient	Amoxicillin 150mg/ml
Formulation	Injectable Solution
Administration Route	Intramuscular
Peak Plasma Concentration (Cmax)	Cattle: 3.45 µg/ml (2.45 hours post-administration) Pigs: 3.54 µg/ml (2 hours post-administration)
Plasma Protein Binding	17%
Excretion Pathways	Kidneys (primary), biliary system, and milk
Withdrawal Period	Cattle and Pigs: 28 days Milk: 4 hours
Storage Conditions	Sealed, protected from light, and out of reach of children
Packaging	100ml/bottle
Shelf Life	3 years

Application Scenarios

Amoxicillin Injection is widely used in veterinary medicine to treat bacterial infections in cattle and pigs. Its primary application is in managing respiratory diseases caused by Mannheimia haemolytica and Pasteurella multocida. These pathogens are prevalent in livestock, particularly in confined environments where close contact increases transmission risk.

The product is also effective in treating infections involving other Gram-positive and Gram-negative bacteria. Its ability to penetrate tissues such as pleural and synovial fluid makes it suitable for conditions like pneumonia, bronchitis, and joint infections. Veterinarians often recommend Amoxicillin Injection as a first-line treatment for acute bacterial infections in livestock.

For farmers and agricultural professionals, Amoxicillin Injection offers a reliable solution for maintaining herd health. Its short withdrawal period for milk (4 hours) allows for efficient production cycles, while the 28-day withdrawal period for meat ensures compliance with food safety regulations. This balance between efficacy and safety is critical for sustainable livestock management.

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a leading manufacturer of veterinary pharmaceuticals, dedicated to developing high-quality products for livestock health. With a focus on innovation and compliance, the company ensures its products meet international standards for safety and efficacy.

As a trusted name in the veterinary industry, Shijiazhuang Shimu Pharmaceutical Co., Ltd. has built a reputation for delivering reliable solutions to farmers and veterinarians. The company’s commitment to research and development has enabled it to produce formulations like Amoxicillin Injection, which address specific challenges in animal healthcare.

The company’s product portfolio includes a range of antibiotics, vaccines, and supportive therapies tailored for different species. By prioritizing quality control and regulatory compliance, Shijiazhuang Shimu Pharmaceutical Co., Ltd. continues to play a vital role in advancing veterinary medicine.

Important Safety Information

Like all penicillins, Amoxicillin Injection may cause hypersensitivity reactions in animals with known allergies to beta-lactams. It is crucial to avoid use in animals with a history of allergic responses to similar antibiotics. Local reactions at the injection site, though rare, may occur and are typically transient.

Users must follow strict guidelines to ensure the safety of both animals and consumers. Milk for human consumption must not be used during treatment, and it is only safe to harvest milk from cattle 96 hours after the last dose. These precautions are essential for maintaining food safety and public health.

Conclusion

Amoxicillin Injection is a critical tool in veterinary medicine, offering effective treatment for bacterial infections in cattle and pigs. Its broad-spectrum activity, favorable pharmacokinetic profile, and compliance with safety standards make it an invaluable asset for livestock producers. Manufactured by Shijiazhuang Shimu Pharmaceutical Co., Ltd., this product exemplifies the company’s commitment to quality and innovation in animal healthcare.

For more information about Amoxicillin Injection and its applications, visit the product page or explore the company website.

References

NIST (National Institute of Standards and Technology) plays a critical role in establishing standards for pharmaceuticals and medical devices. While specific citations for Amoxicillin Injection were not found, NIST’s work in metrology and measurement science ensures the accuracy and reliability of pharmaceutical testing. For more information on NIST’s contributions to healthcare standards, visit https://www.nist.gov.