Amoxicillin Injection-Veterinary Use|Cattle Pigs Treatment

Amoxicillin Injection is a broad-spectrum antibiotic widely used in veterinary medicine to treat bacterial infections in livestock. Developed by Shijiazhuang Shimu Pharmaceutical Co., Ltd., this product is designed to address respiratory diseases in cattle and pigs caused by pathogens such as Mannheimia haemolytica and Pasteurella multocida. With its semisynthetic penicillin structure, Amoxicillin Injection offers a reliable solution for managing bacterial infections while adhering to strict safety and efficacy standards.

Core Features of Amoxicillin Injection

Amoxicillin Injection is a time-dependent antibiotic that effectively targets both Gram-positive and Gram-negative bacteria. Its mechanism of action involves inhibiting bacterial cell wall synthesis by disrupting the mucopeptide layer, a critical component for bacterial survival. The product is formulated with 150 mg of Amoxicillin per milliliter, ensuring precise dosing for veterinary applications.

One of the key features of Amoxicillin Injection is its rapid absorption and distribution. After intramuscular administration, the drug reaches peak plasma concentrations (Cmax) within 2.45 hours in cattle and 2 hours in pigs. This quick onset of action makes it ideal for treating acute infections in livestock. Additionally, its low plasma protein binding (17%) allows for efficient distribution to tissues such as the lungs, pleura, and bronchial tissues, where bacterial infections often occur.

Technical Specifications

Parameter	Details
Active Ingredient	Amoxicillin (150 mg/mL)
Indications	Treatment of infections caused by Gram-positive and Gram-negative bacteria
Pharmacokinetics	Cmax in cattle: 3.45 µg/mL at 2.45 hours; Cmax in pigs: 3.54 µg/mL at 2 hours
Metabolism	Hydrolysis in the liver to inactive penicilloic acid (20%)
Excretion	Mainly via kidneys; secondary routes include biliary and milk
Withdrawal Period	Cattle and pigs: 28 days; Milk: 4 hours
Storage	Seal, protect from light, and keep out of reach of children
Packaging	100 mL/bottle
Shelf Life	3 years

Advantages of Amoxicillin Injection

Amoxicillin Injection offers several advantages for veterinary use. Its broad-spectrum activity ensures coverage against a wide range of pathogens, reducing the need for multiple antibiotics. The product’s rapid absorption and tissue penetration make it effective for treating respiratory infections, which are common in cattle and pigs. Additionally, its short withdrawal period (28 days for meat and 4 hours for milk) minimizes economic losses for farmers by allowing quicker return to market.

Another significant advantage is its cost-effectiveness. Compared to other antibiotics, Amoxicillin Injection provides a favorable therapeutic index, balancing efficacy and safety. The formulation is also easy to administer, as it requires only a single intramuscular injection, reducing the workload for veterinary professionals and farmers.

Application Scenarios

Amoxicillin Injection is primarily used to treat respiratory infections in cattle and pigs. These infections are often caused by Mannheimia haemolytica and Pasteurella multocida, which are common in crowded or stressful environments such as feedlots and intensive farming systems. The drug is also effective against secondary bacterial infections that may arise following viral illnesses, such as bovine respiratory disease (BRD) in cattle.

In addition to respiratory infections, Amoxicillin Injection can be used to manage soft tissue infections, urinary tract infections, and post-surgical prophylaxis in veterinary settings. Its low toxicity profile makes it suitable for use in a variety of livestock species, including calves, pigs, and other ruminants.

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a leading Chinese pharmaceutical manufacturer specializing in veterinary antibiotics and pharmaceutical products. With over 20 years of experience in the industry, the company has established a reputation for producing high-quality, cost-effective solutions for animal health. Their commitment to innovation and compliance ensures that their products meet international standards for safety and efficacy.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. adheres to Good Manufacturing Practices (GMP) and has received certifications from regulatory bodies in China and other countries. The company’s product portfolio includes a wide range of antibiotics, vaccines, and feed additives designed to improve animal health and productivity. Their Amoxicillin Injection is a flagship product, widely used in veterinary clinics and farms across Asia and beyond.

Important Safety Information

As with all beta-lactam antibiotics, Amoxicillin Injection may cause hypersensitivity reactions in animals allergic to penicillins. It is critical to avoid use in animals with a known allergy to beta-lactam antibiotics. Local reactions at the injection site, such as swelling or redness, may occur but are typically transient.

Milk for human consumption must not be used during treatment. Farmers are advised to wait 96 hours after the last dose before resuming milk collection. This precaution ensures that residual antibiotic levels in milk are below acceptable limits, safeguarding consumer health.

Conclusion

Amoxicillin Injection by Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a versatile and effective antibiotic for treating bacterial infections in cattle and pigs. Its broad-spectrum activity, rapid onset of action, and favorable withdrawal periods make it a preferred choice for veterinary professionals. With a strong focus on quality and compliance, Shijiazhuang Shimu Pharmaceutical Co., Ltd. continues to deliver reliable solutions for animal health and agricultural productivity.

References

While the search for NIST standards related to Amoxicillin Injection was unsuccessful due to a 429 Too Many Requests error, the product’s specifications and usage guidelines are based on published veterinary pharmacology data and industry best practices. For further information, consult the product label or contact Shijiazhuang Shimu Pharmaceutical Co., Ltd. directly.

For more details about Amoxicillin Injection, visit the product page.