Amoxicillin Injection-Veterinary Use|Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Amoxicillin Injection is a versatile veterinary amoxicillin injection designed to combat bacterial infections in livestock, particularly cattle and pigs. Developed by Shijiazhuang Shimu Pharmaceutical Co., Ltd., this antibiotic belongs to the amino-penicillin family and is renowned for its broad-spectrum efficacy. This article delves into the amoxicillin injection uses, technical specifications, application scenarios, and the company's commitment to veterinary healthcare.

Product Overview

Amoxicillin Injection is a semisynthetic penicillin that targets both Gram-positive and Gram-negative bacteria. Its mechanism of action involves inhibiting bacterial cell wall synthesis, making it a potent bactericide. The product is formulated to be administered via intramuscular injection, ensuring rapid systemic absorption and therapeutic efficacy. For detailed information, visit the product page.

Key Features and Advantages

1. Broad-Spectrum Antibiotic: Amoxicillin Injection is effective against a wide range of pathogens, including Mannheimia haemolytica and Pasteurella multocida, which are common causes of respiratory infections in cattle and pigs. Its ability to target both Gram-positive and Gram-negative bacteria makes it a preferred choice for veterinary amoxicillin injection.

2. Rapid Onset of Action: After intramuscular administration, the drug reaches peak plasma concentrations (Cmax) within 2–2.45 hours. For cattle, the Cmax is 3.45 µg/ml, while in pigs, it reaches 3.54 µg/ml. This quick absorption ensures prompt therapeutic effects, reducing the duration of illness in affected animals.

3. Tissue Distribution: Amoxicillin distributes efficiently into extracellular compartments, with low plasma protein binding (17%). It achieves therapeutic concentrations in critical tissues such as the lungs, pleura, and bronchial tissues, making it ideal for treating respiratory infections. The drug also diffuses into pleural and synovial fluids, enhancing its efficacy in localized infections.

4. Safety Profile: While generally well-tolerated, Amoxicillin Injection may cause transient local reactions at the injection site. It is contraindicated in animals with known hypersensitivity to beta-lactam antibiotics. Always follow the safety guidelines provided by the manufacturer.

Technical Specifications

Parameter	Details
Composition	150 mg Amoxicillin per ml
Indication	Treatment of bacterial infections caused by Gram-positive and Gram-negative bacteria
Pharmacokinetics	Cmax in cattle: 3.45 µg/ml (2.45 hours post-administration); Cmax in pigs: 3.54 µg/ml (2 hours post-administration)
Metabolism	Metabolized in the liver via hydrolysis of the β-lactam ring, forming inactive penicilloic acid (20%)
Excretion	Primarily via renal excretion; secondary routes include biliary and milk
Withdrawal Period	Cattle and pigs: 28 days; Milk: 4 hours
Storage	Seal, protect from light, and keep out of reach of children
Packaging	100 ml/bottle
Shelf Life	3 years

Application Scenarios

1. Respiratory Infections in Cattle: Amoxicillin Injection is widely used to treat bacterial pneumonia caused by Mannheimia haemolytica and Pasteurella multocida. Its ability to penetrate lung tissues ensures effective eradication of pathogens, reducing mortality rates in herds.

2. Swine Respiratory Diseases: The drug is effective against Pasteurella multocida in pigs, a common cause of swine respiratory disease. Its rapid onset of action and broad-spectrum activity make it a staple in swine health management programs.

3. General Bacterial Infections: Beyond respiratory issues, Amoxicillin Injection is utilized for skin, soft tissue, and urinary tract infections in livestock. Its low protein binding and tissue distribution properties enhance its versatility in treating diverse infections.

Company Background

Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a leading manufacturer of veterinary pharmaceuticals, dedicated to advancing animal health through innovative solutions. With a focus on quality and efficacy, the company ensures its products meet stringent standards for safety and performance. Their commitment to research and development has positioned them as a trusted name in the veterinary industry. Learn more about their products on the company website.

Authoritative Citations

According to the National Institute of Standards and Technology (NIST), the accuracy of pharmaceutical measurements is critical for ensuring drug efficacy and safety. NIST's work in metrology and standardization supports the development of reliable veterinary medications, including antibiotics like Amoxicillin Injection. For further details on NIST's role in pharmaceutical standards, visit the NIST website.

References: 1. National Institute of Standards and Technology (NIST) 2. Amoxicillin Injection Product Page

Conclusion

Amoxicillin Injection by Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a reliable and effective solution for managing bacterial infections in livestock. Its broad-spectrum activity, rapid pharmacokinetics, and safety profile make it an essential tool for veterinarians. By adhering to proper administration protocols and withdrawal periods, farmers and veterinarians can ensure optimal outcomes for their animals. For more information, explore the company's resources and stay informed about the latest advancements in veterinary medicine.