Amoxicillin Injection | Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Amoxicillin Injection is a veterinary antibiotic designed to treat bacterial infections in livestock, particularly in cattle and pigs. Developed by Shijiazhuang Shimu Pharmaceutical Co., Ltd., this product is a critical tool in modern veterinary medicine, offering broad-spectrum efficacy against both Gram-positive and Gram-negative bacteria. Its pharmacokinetic profile ensures rapid distribution to target tissues, making it an essential solution for respiratory infections in animals.

Key Features of Amoxicillin Injection

Amoxicillin Injection belongs to the amino-penicillin family, closely related to ampicillin. It functions as a bactericidal agent, meaning it actively kills bacteria by inhibiting the synthesis and repair of their cell walls. This mechanism is particularly effective against pathogens like Mannheimia haemolytica and Pasteurella multocida, which are common causes of respiratory diseases in cattle and pigs. The product is also time-dependent, requiring consistent dosing to maintain therapeutic levels in the bloodstream.

Advantages of Amoxicillin Injection

One of the standout benefits of Amoxicillin Injection is its broad-spectrum activity, which allows it to combat a wide range of bacterial infections. Its low plasma protein binding (17%) ensures that the drug is rapidly distributed to extracellular compartments, including critical tissues like the lungs, pleura, and bronchial areas. This distribution is vital for treating respiratory conditions effectively. Additionally, the product’s short withdrawal period (28 days for meat and 4 hours for milk) makes it a practical choice for farmers, minimizing disruptions to livestock management.

Technical Specifications

Parameter	Details
Active Ingredient	Amoxicillin (150 mg/ml)
Pharmacokinetic Profile	Cmax in cattle: 3.45 µg/ml (2.45 hours post-administration); Cmax in pigs: 3.54 µg/ml (2 hours post-administration)
Distribution	Primarily extracellular; concentrations in pulmonary and bronchial tissues match plasma levels
Metabolism	Hydrolysis in the liver to inactive penicilloic acid (20%)
Excretion	Primarily via kidneys; secondary routes include biliary and milk
Storage	Sealed, protected from light; shelf life: 3 years
Withdrawal Period	28 days for meat; 4 hours for milk

Application Scenarios

Amoxicillin Injection is widely used in veterinary medicine to treat infections caused by Gram-positive and Gram-negative bacteria. Its primary applications include:

• Respiratory Infections: Effective against Mannheimia haemolytica and Pasteurella multocida in cattle and pigs.
• Systemic Infections: Treats bacterial infections that spread beyond the initial site of infection.
• Post-Operative Care: Prevents secondary infections following surgical procedures in livestock.

The product’s rapid onset of action and high bioavailability make it ideal for managing acute infections in large animals. Farmers and veterinarians rely on its consistent efficacy to maintain herd health and productivity.

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a leading manufacturer of veterinary pharmaceuticals based in China. With a focus on innovation and quality, the company develops products that meet the needs of modern agriculture and animal health. Their commitment to scientific research and regulatory compliance ensures that their products, such as Amoxicillin Injection, are safe, effective, and suitable for global markets.

Usage Guidelines and Safety Information

Before administering Amoxicillin Injection, it is crucial to follow these guidelines:

• Allergy Precautions: Do not use in animals with a known allergy to beta-lactam antibiotics.
• Administration: Shake the bottle well before use. Administer via intramuscular injection as directed by a veterinarian.
• Withdrawal Period: Avoid using milk from treated animals for human consumption for 4 hours after the last dose. Meat should not be used for 28 days post-treatment.

While local reactions at the injection site may occur, they are typically transient and resolve without intervention. Always consult a veterinary professional to ensure proper dosing and minimize the risk of antibiotic resistance.

Why Choose Amoxicillin Injection?

Amoxicillin Injection stands out in the veterinary market due to its efficacy, safety profile, and cost-effectiveness. Its ability to target a wide range of pathogens, combined with a short withdrawal period, makes it a preferred choice for livestock producers. For more information, visit the product page or explore the Shijiazhuang Shimu Pharmaceutical Co., Ltd. website.

Conclusion

Amoxicillin Injection is a vital tool in the fight against bacterial infections in cattle and pigs. With its robust pharmacokinetic properties, broad-spectrum activity, and user-friendly administration, it addresses critical needs in veterinary medicine. By choosing Shijiazhuang Shimu Pharmaceutical Co., Ltd., farmers and veterinarians gain access to a reliable, high-quality product that supports animal health and agricultural productivity.

References

While specific citations from NIST could not be retrieved due to technical limitations, the information provided aligns with standard veterinary pharmacological principles. For further details, refer to authoritative sources such as the U.S. Food and Drug Administration (FDA) or the World Organisation for Animal Health (WOAH).