Amoxicillin Injection: Veterinary Use & Pharmacokinetics | Shimu Pharmaceutical

Introduction

Amoxicillin Injection is a broad-spectrum antibiotic widely used in veterinary medicine. This article provides an in-depth exploration of its pharmacokinetic properties, applications, and technical specifications.

Pharmacokinetic Properties

Amoxicillin, a member of the amino-penicillin family, exhibits bactericidal activity against both Gram-positive and Gram-negative bacteria. It inhibits bacterial cell wall synthesis by targeting the mucopeptide layer (Learn more).

Key Specifications

Parameter	Value
Active Ingredient	Amoxicillin 150mg/ml
Administration Route	Intramuscular
Cmax in Cattle	3.45 µg/ml (2.45h)
Cmax in Pigs	3.54 µg/ml (2h)
Half-Life	1.3 hours (cattle), 1.2 hours (pigs)

Applications in Veterinary Medicine

Amoxicillin Injection is indicated for respiratory infections caused by Mannheimia haemolytica and Pasteurella multocida in cattle and pigs. Its efficacy against these pathogens makes it a critical tool in livestock health management.

Adverse Reactions and Precautions

• Hypersensitivity reactions may occur in animals allergic to beta-lactams.
• Local injection site reactions are rare but possible.
• Milk withdrawal period: 4 hours; meat withdrawal period: 28 days.

Company Background

Manufactured by Shijiazhuang Shimu Pharmaceutical Co., Ltd., a leading Chinese veterinary pharmaceutical company. The product is packaged in 100ml bottles with a 3-year shelf life.

References

1. National Institute of Standards and Technology (NIST). https://www.nist.gov