Ciprofloxacin Hydrochloride Soluble Powder for Veterinary Use Only: field notes, specs, and real-world lessons

I first saw the production line in the South District of Shangzhuang Industry Zone, Shijiazhuang, Hebei—lots of stainless steel, a surprising quiet, and a QC lab that didn’t feel showy, just tidy and busy. That’s where this veterinary powder is made: Ciprofloxacin Hydrochloride Soluble Powder For Veterinary Use Only. It targets bacterial and mycoplasma infections (fluoroquinolone class). In fact, it’s a pragmatic choice in places where regulations permit its use and antimicrobial stewardship is strictly observed.

What’s trending (and what buyers quietly ask)

Two threads define 2025 procurement: faster dissolution for medicators and transparent QC. Many customers say they’re done with clumping powders. Also, to be honest, veterinary teams want proof—assay data, stability, and traceability. This product leans into that, and, yes, customization is on the table (strength, pack sizes, labeling).

Technical snapshot and specs

Composition per 1 g: Ciprofloxacin 20/50/500 mg; excipients optimized for solubility. Indications: fluoroquinolone antibiotic; for bacterial and mycoplasma infections (use only under veterinary direction; observe local regulations and withdrawal periods).

Process flow (brief but practical)

• Materials: Ciprofloxacin HCl API + pharma‑grade carriers for wetting/dissolution.
• Methods: Pre‑blend → high‑shear mix → sieving (D90 control) → in‑process assay → unit dosing.
• Testing: HPLC assay/impurities, moisture (LOD), dissolution, pH, microbial limits, stability (accelerated/long‑term).
• Service life: sealed product ≈24 months; opened packs—close promptly with desiccant.
• Industries: integrators, contract growers, vet clinics, government tenders (where lawful).

Vendor comparison (quick reality check)

Numbers are indicative; ≈ means typical ranges based on recent orders—real‑world use may vary.

Applications, dosing, stewardship

Use this veterinary powder via drinking water systems or medicators, per a veterinarian’s diagnosis and local law. Typical field dosing (example only): 10–20 mg/kg/day for 3–5 days—but I’ll stress it again: follow licensed veterinary direction and official withdrawal times. Where regulations restrict fluoroquinolones (some poultry markets do), choose alternatives.

Customization and paperwork

• Strengths: 2%, 5%, 50% w/w equivalents; custom ratios on request.
• Packaging: single‑use sachets to bulk; multilingual labeling.
• Docs: COA, MSDS, method summaries, stability protocols, GMP certificates.

Case notes (anecdotal, but useful)

• Broiler complex (Southeast Asia): after waterline sanitation and switch to this veterinary powder, medicator clogging dropped; E. coli counts fell; mortality improved by ≈0.3% over two cycles. Correlation isn’t causation, but the team was happy.
• Mixed swine farm (Eastern Europe): mycoplasma-associated respiratory signs—veterinarian supervised a 5‑day water program; producers reported quicker feed rebound and fewer retreated pens.

Compliance and test data (abridged)

Recent lots: assay 100.3% (HPLC), related substances within pharmacopeial limits, moisture 2.1%, dissolution pass (≤3 min), microbial limits pass. Stability: 6M accelerated and 24M long‑term trending within spec, aligned with VICH stability guidelines.

Antimicrobial stewardship matters—reserve fluoroquinolones for indicated cases, culture/susceptibility when feasible, and follow WOAH/WHO guidance.

Authoritative references

1. VICH GL3(R) and GL10/GL27: Stability testing for new veterinary drug products (VICH).
2. WOAH (OIE) List of antimicrobial agents of veterinary importance and stewardship guidance.
3. WHO Critically Important Antimicrobials for Human Medicine (fluoroquinolones category).
4. USP/Ph. Eur. monographs for Ciprofloxacin and related substances testing.