Oxytetracycline Injection
Oxytetracycline is active against a wide range of Gram positive and Gram negative pathogenic bacteria, and certain Rickettsia. Oxytetracycline is a bacteriostatic antibiotic that inhibits protein synthesis in susceptible bacteria. Inside the cell it binds irreversibly to receptors on the 30S subunit of the bacterial ribosome where it interferes with the binding of the amino-acyl transfer RNA to the acceptor site on the messenger RNA ribosome complex. This effectively prevents the addition of the amino acids to the elongating peptide chain, inhibiting protein synthesis.
Oxytetracycline is widely distributed in the body, including to the kidneys, liver, lungs and muscle, though only small quantities are distributed to the CSF. The placenta is readily passed by oxytetracycline and concentration in the fetal blood may reach that of the maternal circulation. Oxytetracycline apparently is not metabolised in vivo and is eliminated primarily unchanged, via glomerular filtration. It is also excreted into the GI tract via both biliary and non-biliary routes and may become inactive after chelation with faecal material.
Dosage And Administration:By intramuscular injection.
Cattle, sheep, goats and pigs: 1ml/ 10-20kg body weight, 10-20mg/kg body weight.
Adverse Reaction:Tetracyclines may cause renal tubular necrosis at high doses, but this is rare with recommended doses. Tetracyclines can affect bone and teeth formation in young animals. Hepatoxicity may occur at high doses in susceptible individuals. Oxytetracycline administration to horses has been associated with colic and diarrhea. Anti-metabolism- Tetracyclines can cause azotemia, which can be aggravated by the presence of steroids. These drugs can also cause metabolic acidosis and electrolyte imbalance.
Special Warnings:1.This product should be sealed away from light and kept in a cool and dark dry place. Avoid sun exposure. Do not use metal containers for medicine.
2.Sometimes gastroenteritis can occur in horses after injection, so it should be used with caution.
3.Do not use it when the liver and kidney function of animals are seriously damaged.
Withdrawal Period:Meat: 28 days.
Milk: 7 days.
Storage:Seal and store in a cool and dark place, protect from light.
Keep out of reach of children.
Packaging:100ml/250ml/bottle
Shelf Life:3 years.