Amoxicillin Injection - Shijiazhuang Shimu Pharmaceutical Co., Ltd.|Veterinary Antibiotic, Rapid Efficacy

Amoxicillin Injection is a critical veterinary medication designed to combat bacterial infections in livestock, particularly in cattle and pigs. This article provides an in-depth analysis of its pharmacokinetic properties, therapeutic applications, technical specifications, and the company behind its production. Whether you are a veterinarian, livestock manager, or pharmaceutical professional, this guide offers essential insights into the efficacy and safety of Amoxicillin Injection.

Pharmacokinetic Properties of Amoxicillin Injection

Amoxicillin, a semisynthetic penicillin, belongs to the amino-penicillin family and is structurally related to ampicillin. It acts as a bactericidal agent, effectively targeting both Gram-positive and Gram-negative bacteria by inhibiting the synthesis and repair of bacterial cell walls. Its mechanism of action is time-dependent, making it particularly effective against pathogens such as Mannheimia haemolytica and Pasteurella multocida, which are common causes of respiratory diseases in cattle and pigs.

Key Pharmacokinetic Data

• Cattle: Maximum plasma concentration (Cmax) of 3.45 µg/ml is achieved 2.45 hours after intramuscular administration.
• Pigs: Cmax of 3.54 µg/ml is reached 2 hours post-injection.
• Amoxicillin is predominantly distributed in the extracellular compartment, with low plasma protein binding (17%), allowing it to penetrate tissues such as the lungs, pleura, and bronchial tissues effectively.
• Metabolism occurs in the liver via hydrolysis of the β-lactam ring, producing inactive penicilloic acid (20%).
• Excretion primarily occurs via the kidneys, with secondary routes including the biliary system and milk.

Therapeutic Applications and Indications

Amoxicillin Injection is indicated for the treatment of infections caused by susceptible Gram-positive and Gram-negative bacteria. Its broad-spectrum activity makes it a preferred choice for managing respiratory infections in livestock, including those caused by amoxicillin injection uses in cattle and pigs. The drug’s ability to achieve therapeutic concentrations in critical tissues ensures effective eradication of pathogens, reducing the risk of complications and improving recovery rates.

Veterinary amoxicillin injection is particularly valuable in large-scale farming operations where rapid and reliable treatment is essential. Its formulation allows for easy administration via intramuscular injection, ensuring consistent dosing and minimizing the risk of treatment failure due to improper delivery.

Advantages of Amoxicillin Injection

Amoxicillin Injection offers several advantages that make it a preferred choice in veterinary medicine:

• High Bioavailability: The drug’s rapid absorption and distribution ensure quick onset of action, which is critical in treating acute infections.
• Minimal Side Effects: While hypersensitivity reactions are possible, the incidence of adverse effects is generally low, especially when the product is used as directed.
• Cost-Effective: Amoxicillin Injection provides an economical solution for managing bacterial infections in livestock, reducing the overall cost of treatment and improving profitability for farmers.
• Regulatory Compliance: The product adheres to strict quality standards, ensuring safety and efficacy for both animals and end consumers.

Technical Specifications Table

Parameter	Details
Composition	150 mg Amoxicillin per mL
Indication	Treatment of infections caused by Gram-positive and Gram-negative bacteria
Withdrawal Period	Cattle and pigs: 28 days; Milk: 4 hours
Storage	Seal and protect from light; Keep out of reach of children
Packaging	100 mL/bottle
Shelf Life	3 years

Important Safety Information

As with all penicillins, Amoxicillin Injection may cause hypersensitivity reactions in animals with a known allergy to beta-lactams. Local reactions at the injection site, though rare, may occur and are typically transient. It is crucial to follow the recommended withdrawal periods to ensure the safety of milk and meat for human consumption.

Amoxicillin injection 1g should not be used in animals with a history of allergic reactions to penicillins. Farmers and veterinarians are advised to monitor animals closely during treatment and report any adverse effects to the relevant authorities.

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. (石家庄石牧药业有限公司) is a reputable manufacturer of veterinary pharmaceuticals, dedicated to providing high-quality solutions for livestock health. With a focus on innovation and compliance, the company ensures that its products meet the stringent requirements of the veterinary industry.

As a leader in the field, Shijiazhuang Shimu Pharmaceutical Co., Ltd. has established itself as a trusted name in the production of antibiotics and other essential veterinary medicines. The company’s commitment to quality is reflected in its adherence to international standards, ensuring that products like veterinary amoxicillin injection are safe, effective, and reliable.

Conclusion

Amoxicillin Injection is a vital tool in the management of bacterial infections in cattle and pigs, offering a combination of efficacy, safety, and cost-effectiveness. Its pharmacokinetic profile ensures rapid and sustained therapeutic action, while its compliance with regulatory standards guarantees the safety of both animals and consumers. For those seeking a reliable solution for livestock health, Shijiazhuang Shimu Pharmaceutical Co., Ltd. provides a trusted source of high-quality veterinary medications.

References

1. National Institute of Standards and Technology (NIST). (n.d.). Retrieved from https://www.nist.gov/

2. Shijiazhuang Shimu Pharmaceutical Co., Ltd. (n.d.). Amoxicillin Injection Product Page. Retrieved from https://www.skyvetpharm.com/amoxicillin-injection.html