Amoxicillin Injection - Shijiazhuang Shimu Pharmaceutical Co., Ltd.|Veterinary Antibiotic Treatment & Broad-Spectrum Solutions

Product Overview

Amoxicillin Injection is a semisynthetic penicillin antibiotic designed for veterinary use, offering broad-spectrum activity against both Gram-positive and Gram-negative bacteria. Manufactured by Shijiazhuang Shimu Pharmaceutical Co., Ltd., this product is a critical solution for treating bacterial infections in livestock, including cattle and pigs. For more details, visit the product page.

Pharmacokinetic Properties

Understanding the pharmacokinetics of Amoxicillin Injection is essential for its effective application. The drug exhibits the following characteristics:

• Bactericidal Action: Amoxicillin inhibits bacterial cell wall synthesis, making it a potent bactericide against a wide range of pathogens.
• Time-Dependent Antibiotic: Its efficacy is closely related to the duration of exposure to the bacteria, necessitating proper dosing schedules.
• Pharmacokinetic Data:
  • Cattle: Peak plasma concentration (Cmax) of 3.45 µg/ml is achieved 2.45 hours post-intramuscular administration.
  • Pigs: Cmax of 3.54 µg/ml is reached 2 hours after administration.
• Distribution: Amoxicillin distributes primarily to the extracellular compartment, with low plasma protein binding (17%), allowing it to penetrate tissues such as pulmonary, pleural, and bronchial tissues effectively.
• Metabolism and Excretion: The drug is metabolized in the liver, with 20% converted to inactive penicilloic acid. It is mainly excreted via the kidneys, with secondary excretion through the biliary route and milk.

Applications and Indications

Amoxicillin Injection is indicated for the treatment of bacterial infections caused by susceptible organisms in veterinary medicine. Key applications include:

• Respiratory Infections: Effective against Mannheimia haemolytica and Pasteurella multocida, which are common pathogens in cattle and pigs.
• Systemic Infections: Treats infections caused by Gram-positive and Gram-negative bacteria, including skin, soft tissue, and urinary tract infections.
• Preventive Use: May be used prophylactically in high-risk environments to prevent bacterial outbreaks.

For a detailed list of indications, refer to the product specifications.

Advantages and Benefits

The Amoxicillin Injection offers several advantages that make it a preferred choice in veterinary medicine:

• Broad-Spectrum Activity: Effective against a wide range of bacterial pathogens, reducing the need for multiple antibiotics.
• Fast Onset of Action: Rapid absorption and distribution ensure quick therapeutic effects.
• Minimal Side Effects: Generally well-tolerated, with adverse reactions being rare and typically mild.
• Cost-Effective: Provides a balance between efficacy and affordability, making it accessible for large-scale use.

Safety and Precautions

While Amoxicillin Injection is generally safe, certain precautions must be observed:

• Allergic Reactions: Hypersensitivity (allergy) may occur in animals with a known history of beta-lactam allergies. Always perform a patch test before administration.
• Local Reactions: Transient injection site reactions may occur but are typically self-limiting.
• Withdrawal Periods:
  • Cattle and Pigs: 28 days post-treatment.
  • Milk: 4 hours post-treatment.
• Storage: Store in a sealed container111, protected from light, and out of reach of children. The shelf life is 3 years.

Product Specifications

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a reputable manufacturer of veterinary pharmaceuticals, dedicated to providing high-quality products for animal health. With a focus on innovation and compliance with international standards, the company ensures that its products meet rigorous safety and efficacy criteria. Their commitment to research and development has positioned them as a trusted partner in the veterinary industry.

For more information about the company, visit the Shijiazhuang Shimu Pharmaceutical Co., Ltd. website.

Expertise and Authority

The development and application of antibiotics like Amoxicillin Injection are guided by principles of precision and safety, as emphasized by organizations such as the National Institute of Standards and Technology (NIST). While NIST primarily focuses on measurement science and standards, its work in ensuring the accuracy of scientific data aligns with the importance of reliable pharmaceutical products. For more information on NIST's role in advancing technology, visit the NIST website.

Conclusion

Amoxicillin Injection by Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a vital tool in the treatment of bacterial infections in veterinary medicine. Its broad-spectrum activity, favorable pharmacokinetic profile, and safety record make it an essential product for livestock health. By adhering to strict quality standards and prioritizing animal welfare, the company continues to contribute to the advancement of veterinary care.