Amoxicillin Injection - Shijiazhuang Shimu Pharmaceutical Co., Ltd.|Veterinary Treatment,Broad-Spectrum Antibiotic

Amoxicillin Injection is a critical veterinary pharmaceutical product designed to combat bacterial infections in livestock. This article provides an in-depth analysis of its pharmacokinetic properties, technical specifications, applications, and the company behind its production. Whether you are a veterinarian, farmer, or pharmaceutical professional, this guide offers essential insights into the efficacy and safety of this antibiotic.

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Product Overview

Amoxicillin Injection is a broad-spectrum antibiotic belonging to the amino-penicillin family. It is specifically formulated for veterinary use to treat bacterial infections in cattle and pigs. The product is available in a 100ml bottle, with a shelf life of three years when stored properly. Its active ingredient, amoxicillin, is a bactericidal agent that targets both Gram-positive and Gram-negative bacteria by inhibiting bacterial cell wall synthesis.

Pharmacokinetic Properties

Understanding the pharmacokinetics of Amoxicillin Injection is crucial for optimizing its therapeutic effects. Here’s a detailed breakdown of its behavior in the body:

• Peak Concentration (Cmax): In cattle, Cmax of 3.45 µg/ml is achieved 2.45 hours post-intramuscular administration. In pigs, the peak concentration reaches 3.54 µg/ml within 2 hours.
• Distribution: Amoxicillin distributes primarily to the extracellular compartment, facilitated by its low plasma protein binding (17%). It accumulates in pulmonary, pleural, and bronchial tissues, with concentrations similar to plasma levels.
• Metabolism: The drug undergoes hepatic hydrolysis of the β-lactam ring, converting it into inactive penicilloic acid (20% of the original compound).
• Excretion: Amoxicillin is mainly excreted via the kidneys in its active form, with secondary excretion through the biliary route and milk.

Technical Specifications

Parameter	Details
Active Ingredient	Amoxicillin 150mg/ml
Indications	Treatment of infections caused by Gram-positive and Gram-negative bacteria
Withdrawal Period	Cattle and Pigs: 28 days; Milk: 4 hours
Storage	Seal and protect from light. Keep out of reach of children.
Packaging	100ml/bottle
Shelf Life	3 years

Applications in Veterinary Medicine

Amoxicillin Injection is widely used in veterinary settings to address respiratory infections in cattle and pigs. It is particularly effective against the following pathogens:

• Mannheimia haemolytica – A primary cause of bovine respiratory disease.
• Pasteurella multocida – Responsible for respiratory infections in both cattle and pigs.

Its efficacy in targeting these bacteria makes it a preferred choice for treating conditions such as pneumonia and other bacterial infections in livestock. The drug’s ability to penetrate tissues and fluids ensures rapid and sustained therapeutic action.

Advantages of Amoxicillin Injection

Several factors contribute to the widespread use of Amoxicillin Injection in veterinary medicine:

• Broad-Spectrum Activity: Effective against a wide range of bacteria, reducing the need for multiple medications.
• Fast Onset of Action: Achieves therapeutic concentrations quickly, ensuring prompt treatment of infections.
• Low Protein Binding: Enhances tissue distribution and effectiveness in extracellular spaces.
• Easy Administration: Available in an injectable form, suitable for intramuscular use in large animals.

Important Safety Information

While Amoxicillin Injection is generally safe, certain precautions must be observed:

• Allergic Reactions: As with all penicillins, hypersensitivity reactions may occur. It should not be used in animals with a known allergy to β-lactam antibiotics.
• Local Reactions: Transient injection site reactions may occur but are typically mild.
• Milk Withdrawal: Milk from treated animals must not be used for human consumption during treatment. For cattle, a 96-hour withdrawal period is required post-treatment.

Always follow the manufacturer’s guidelines and consult a veterinarian for proper dosing and administration.

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a leading manufacturer of veterinary pharmaceuticals, dedicated to providing high-quality solutions for animal health. With a focus on innovation and compliance with international standards, the company ensures that its products meet rigorous safety and efficacy criteria. Their commitment to research and development has positioned them as a trusted name in the veterinary industry.

For more information about the company’s mission and products, visit Shijiazhuang Shimu Pharmaceutical Co., Ltd..

References and Authoritative Sources

The information provided in this article aligns with the standards and research methodologies promoted by the National Institute of Standards and Technology (NIST). NIST plays a pivotal role in advancing scientific and technological innovation through precise measurements and standards, which are critical for pharmaceutical development and quality control. For further insights into NIST’s contributions to scientific research, visit NIST’s official website.

Conclusion

Amoxicillin Injection is an essential tool in veterinary medicine, offering effective treatment for bacterial infections in livestock. Its pharmacokinetic profile, broad-spectrum activity, and safety profile make it a reliable choice for veterinarians and farmers. By adhering to proper usage guidelines and storage conditions, users can maximize its therapeutic benefits while ensuring the safety of both animals and consumers.

Additional Resources

• amoxicillin injection – Explore detailed product information and usage guidelines.
• veterinary amoxicillin injection – Learn about other veterinary pharmaceutical products.
• amoxicillin injection for veterinary use – Discover applications and case studies.
• amoxicillin injection uses – Find answers to common questions about its application.
• amoxicillin injection 1g – Review specifications and dosage information.

References

1. National Institute of Standards and Technology (NIST). https://www.nist.gov/