Amoxicillin Injection-Shijiazhuang Shimu Pharmaceutical Co., Ltd.|Veterinary Use&Broad-Spectrum Efficacy

Introduction

Amoxicillin Injection is a critical pharmaceutical product designed for the treatment of bacterial infections in veterinary medicine. As a broad-spectrum antibiotic, it belongs to the amino-penicillin family, offering efficacy against both Gram-positive and Gram-negative bacteria. This article delves into the pharmacokinetic properties, technical specifications, applications, safety considerations, and the company background of this essential medication. For more information, visit the product page or learn about the company at Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Pharmacokinetic Properties

Amoxicillin Injection is a semisynthetic penicillin known for its bactericidal action. It inhibits bacterial cell wall synthesis by targeting the mucopeptide layer, making it effective against a wide range of pathogens. The drug is particularly active against Mannheimia haemolytica and Pasteurella multocida, which are common causes of respiratory infections in cattle and pigs. Learn more about its uses.

Key Pharmacokinetic Data

• Maximum Concentration (Cmax): 3.45 µg/ml in cattle (2.45 hours post-administration) and 3.54 µg/ml in pigs (2 hours post-administration).
• Distribution: Amoxicillin is primarily distributed in the extracellular compartment, with low plasma protein binding (17%). It reaches similar concentrations in pulmonary, pleural, and bronchial tissues as in plasma.
• Metabolism: The drug is biotransformed in the liver via hydrolysis of the β-lactam ring, forming inactive penicilloic acid (20% of the original compound).
• Excretion: Mainly via the kidneys in active form, with secondary excretion through the biliary route and milk.

Technical Specifications

Applications in Veterinary Medicine

Amoxicillin Injection is widely used in veterinary settings to combat bacterial infections. Its efficacy against Mannheimia haemolytica and Pasteurella multocida makes it a go-to treatment for respiratory diseases in cattle and pigs. Additionally, the drug's time-dependent mechanism ensures sustained antibacterial activity, reducing the risk of resistance development. For detailed usage guidelines, refer to the product documentation.

Safety and Adverse Reactions

While Amoxicillin Injection is generally well-tolerated, it is essential to note the following precautions:

• Hypersensitivity: All penicillins, including amoxicillin, may cause allergic reactions. It should not be used in animals with known β-lactam allergies.
• Local Reactions: Transient injection site reactions may occur but are typically mild.
• Milk Withdrawal: Milk for human consumption must be avoided during treatment. Cattle can resume milk production after 96 hours post-last dose.

For further safety information, consult the product page.

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a reputable manufacturer of veterinary pharmaceuticals, dedicated to delivering high-quality medications for animal health. With a focus on innovation and compliance, the company ensures its products meet stringent safety and efficacy standards. Their commitment to research and development has established them as a trusted name in the industry. Learn more about their mission and products at Shijiazhuang Shimu Pharmaceutical Co., Ltd..

Conclusion

Amoxicillin Injection is a vital tool in veterinary medicine, offering broad-spectrum antibacterial activity and a favorable safety profile. Its pharmacokinetic advantages, such as rapid absorption and distribution, make it effective for treating respiratory infections in livestock. By adhering to proper usage guidelines and withdrawal periods, veterinarians can maximize its therapeutic benefits. For more insights into this product, visit the product page or explore the company's offerings at Shijiazhuang Shimu Pharmaceutical Co., Ltd..

References

NIST (National Institute of Standards and Technology) plays a critical role in establishing measurement standards that ensure the accuracy and reliability of pharmaceutical products. While this article focuses on Amoxicillin Injection, the principles of precision and quality control emphasized by NIST are foundational to the development of such medications. For more information, visit the NIST website.