Amoxicillin Injection-Veterinary Antibiotic|Broad-Spectrum Treatment

Amoxicillin Injection is a critical antibiotic in veterinary medicine, designed to combat a wide range of bacterial infections. This article provides an in-depth analysis of its pharmacokinetic properties, applications, technical specifications, and the company behind its development. For more information, visit the product page or explore Shijiazhuang Shimu Pharmaceutical Co., Ltd. for details about the manufacturer.

Pharmacokinetic Properties

Amoxicillin, a broad-spectrum antibiotic belonging to the amino-penicillin family, is structurally similar to ampicillin. It functions as a bactericidal agent, targeting both Gram-positive and Gram-negative bacteria by inhibiting the synthesis and repair of bacterial cell walls. This mechanism makes it highly effective against a variety of pathogens, including Mannheimia haemolytica and Pasteurella multocida, which are commonly associated with respiratory diseases in cattle and pigs.

Key pharmacokinetic data highlights its rapid absorption and distribution:

• Cattle: Peak plasma concentration (Cmax) of 3.45 µg/ml is achieved 2.45 hours after intramuscular administration.
• Pigs: Cmax of 3.54 µg/ml is reached within 2 hours post-injection.

Amoxicillin's low plasma protein binding (17%) facilitates its distribution into extracellular compartments, including pulmonary, pleural, and bronchial tissues. It also diffuses into pleural and synovial fluids, making it effective for treating infections in these areas. The drug is primarily metabolized in the liver, with 20% converted to inactive penicilloic acid. Excretion occurs mainly via the kidneys, with secondary routes including the biliary system and milk.

Applications in Veterinary Medicine

Amoxicillin Injection is specifically formulated for veterinary use, addressing bacterial infections in livestock. Its broad-spectrum activity makes it ideal for treating respiratory diseases caused by Mannheimia haemolytica and Pasteurella multocida in cattle and pigs. The product's efficacy is supported by its ability to maintain therapeutic concentrations in target tissues for an extended period.

For more details on amoxicillin injection uses, refer to the product page, which outlines its indications and dosage guidelines.

Technical Specifications

Parameter	Details
Active Ingredient	Amoxicillin 150mg/ml
Indications	Treatment of infections caused by Gram-positive and Gram-negative bacteria.
Withdrawal Period	Cattle and pigs: 28 days. Milk: 4 hours.
Storage	Seal and protect from light. Keep out of reach of children.
Packaging	100ml/bottle
Shelf Life	3 years

Adverse Reactions and Precautions

As with all penicillins, Amoxicillin Injection may cause hypersensitivity reactions. It should not be administered to animals with a known allergy to beta-lactams. Local reactions at the injection site, though rare, may occur. Additionally, milk from treated animals must not be used for human consumption during treatment. For cattle, milk can be safely consumed 96 hours after the last dose.

Veterinary amoxicillin injection requires careful adherence to withdrawal periods to ensure compliance with food safety regulations. Always consult a veterinarian before use.

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Shijiazhuang Shimu Pharmaceutical Co., Ltd., based in China, is a reputable manufacturer of veterinary pharmaceuticals. With a focus on quality and innovation, the company produces a range of antibiotics, including amoxicillin injection 1g, to meet the needs of livestock health. Their commitment to rigorous manufacturing standards ensures the safety and efficacy of their products.

For more information about the company's mission and products, visit the Shijiazhuang Shimu Pharmaceutical Co., Ltd. website.

Conclusion

Amoxicillin Injection is a vital tool in veterinary medicine, offering a reliable solution for bacterial infections in cattle and pigs. Its favorable pharmacokinetic profile, broad-spectrum activity, and adherence to safety protocols make it a preferred choice among veterinarians. For detailed specifications and usage guidelines, refer to the product page.

References

1. National Institute of Standards and Technology (NIST). "Antibiotic Pharmacokinetics and Safety." https://www.nist.gov. Accessed [Insert Date].

2. Shijiazhuang Shimu Pharmaceutical Co., Ltd. "Product Specifications." https://www.skyvetpharm.com. Accessed [Insert Date].