Amoxicillin Injection-Veterinary Antibiotic for Cattle & Pigs | Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Amoxicillin Injection is a critical solution in veterinary medicine, offering broad-spectrum antibacterial efficacy for livestock. Developed by Shijiazhuang Shimu Pharmaceutical Co., Ltd., this product is designed to address bacterial infections in cattle and pigs, ensuring animal health and productivity. This article provides a comprehensive overview of its features, advantages, technical specifications, application scenarios, and the company's background.

Product Features

Amoxicillin Injection belongs to the amino-penicillin family, closely related to ampicillin. It functions as a bactericidal antibiotic, targeting both Gram-positive and Gram-negative bacteria. Its mechanism involves inhibiting bacterial cell wall synthesis and repair, making it a potent treatment for respiratory infections in livestock. The product is also time-dependent, requiring consistent dosing to maintain therapeutic levels.

Key features include:

• Broad-spectrum activity: Effective against a wide range of bacteria, including Mannheimia haemolytica and Pasteurella multocida in cattle and pigs.
• Fast absorption: Achieves peak plasma concentrations (Cmax) within 2–2.45 hours after intramuscular administration.
• Low protein binding: 17% plasma protein binding allows for better tissue distribution.
• Renal excretion: Primarily eliminated via the kidneys, with secondary excretion through bile and milk.

Advantages of Amoxicillin Injection

Amoxicillin Injection offers several advantages for veterinary use:

• Targeted therapy: Specifically designed to combat respiratory pathogens in livestock, reducing the risk of secondary infections.
• Quick onset of action: Rapid absorption ensures timely treatment of acute infections.
• Cost-effective: Provides high therapeutic value with a relatively low production cost, making it accessible for farmers and veterinarians.
• Regulatory compliance: Manufactured under strict quality control standards, ensuring safety and efficacy.

Technical Specifications

Parameter	Details
Active Ingredient	Amoxicillin 150mg/ml
Formulation	Injectable solution
Administration Route	Intramuscular
Peak Plasma Concentration (Cmax)	3.45 µg/ml (cattle), 3.54 µg/ml (pigs)
Time to Cmax	2.45 hours (cattle), 2 hours (pigs)
Protein Binding	17%
Metabolism	Liver hydrolysis to inactive penicilloic acid (20%)
Excretion	Renal (main), biliary, and milk
Withdrawal Period	28 days (cattle/pigs), 4 hours (milk)
Storage	Sealed, protected from light, out of reach of children
Packaging	100ml/bottle
Shelf Life	3 years

Application Scenarios

Amoxicillin Injection is widely used in veterinary practice for treating bacterial infections in cattle and pigs. Its primary applications include:

• Respiratory infections: Effective against Mannheimia haemolytica and Pasteurella multocida, common causes of bovine respiratory disease and swine pneumonia.
• Systemic infections: Targets bacteria that spread through the bloodstream, such as those causing septicemia or abscesses.
• Post-surgical prophylaxis: Prevents bacterial contamination after surgical procedures in livestock.
• Feedlot health management: Reduces the incidence of infectious diseases in crowded, high-stress environments.

According to the National Institute of Standards and Technology (NIST), proper antibiotic use in veterinary medicine is critical for maintaining public health and preventing antimicrobial resistance. Amoxicillin Injection aligns with these principles by targeting specific pathogens without unnecessary broad-spectrum coverage.

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a leading manufacturer of veterinary pharmaceuticals based in China. With a focus on innovation and quality, the company produces a range of antibiotics, vaccines, and other veterinary products to support global animal health. Their commitment to research and development ensures that their products meet international standards for safety and efficacy.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. adheres to NIST guidelines for pharmaceutical manufacturing, emphasizing precision in formulation and rigorous testing. This dedication to excellence has earned the company a reputation for reliability in the veterinary industry.

Adverse Reactions and Safety Precautions

While Amoxicillin Injection is generally safe, it may cause adverse reactions in sensitive animals. Common side effects include:

• Hypersensitivity: Allergic reactions (e.g., swelling, difficulty breathing) in animals with a known beta-lactam allergy.
• Local irritation: Transient injection site reactions, such as redness or swelling.

NIST emphasizes the importance of proper dosing and monitoring to minimize risks. Users should follow these precautions:

• Shake the solution well before use.
• Do not administer to animals with a history of beta-lactam allergies.
• Restrict milk for human consumption during treatment (4-hour withdrawal period).
• Store in a cool, dry place away from direct light.

Conclusion

Amoxicillin Injection by Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a vital tool in veterinary medicine, offering effective treatment for bacterial infections in cattle and pigs. Its broad-spectrum activity, rapid absorption, and low toxicity make it a preferred choice for livestock health management. By adhering to strict quality standards and safety protocols, the product ensures both animal welfare and compliance with regulatory requirements.

For more information about Amoxicillin Injection or to explore other veterinary pharmaceutical solutions, visit Skyvetpharm.

References

1. National Institute of Standards and Technology (NIST). (n.d.). Antimicrobial Resistance and Veterinary Medicine. Retrieved from https://www.nist.gov/

2. Shijiazhuang Shimu Pharmaceutical Co., Ltd. (n.d.). Product Specifications for Amoxicillin Injection. Retrieved from https://www.skyvetpharm.com/amoxicillin-injection.html