Amoxicillin Injection-Veterinary Antibiotic|Broad-Spectrum Bacterial Infections

Amoxicillin Injection, produced by Shijiazhuang Shimu Pharmaceutical Co., Ltd., is a semisynthetic penicillin antibiotic designed to treat bacterial infections in livestock. This article provides an in-depth analysis of its pharmacokinetic properties, clinical applications, technical specifications, and usage guidelines. For detailed product information, visit the Amoxicillin Injection product page.

Pharmacokinetic Properties

Amoxicillin is a veterinary amoxicillin injection with a broad spectrum of activity against both Gram-positive and Gram-negative bacteria. It works by inhibiting bacterial cell wall synthesis, making it a bactericidal agent. However, its efficacy is limited by susceptibility to beta-lactamases, enzymes produced by certain bacteria to inactivate penicillins.

Amoxicillin injection uses include treating respiratory infections in cattle and pigs caused by Mannheimia haemolytica, Pasteurella multocida, and other pathogens. Its time-dependent mechanism of action requires consistent drug concentrations to maintain therapeutic efficacy.

Key Pharmacokinetic Data

Parameter	Cattle	Pigs
Cmax (peak concentration)	3.45 µg/ml	3.54 µg/ml
Time to Cmax	2.45 hours	2 hours
Plasma Protein Binding	17%	17%
Excretion Route	Kidneys (primary), biliary (secondary)	Kidneys (primary), biliary (secondary)

Amoxicillin distributes widely into extracellular fluids, including pulmonary, pleural, and bronchial tissues. Its low plasma protein binding allows it to achieve therapeutic concentrations in infected tissues. However, it undergoes hepatic metabolism, with 20% converted to inactive penicilloic acid.

Clinical Applications and Advantages

Amoxicillin injection for veterinary use is particularly effective against respiratory tract infections in livestock. Its rapid absorption and distribution make it ideal for treating conditions like bovine respiratory disease and swine pneumonia. The product's formulation ensures sustained therapeutic levels, reducing the need for frequent dosing.

Key advantages include:

• Broad-spectrum activity against common pathogens
• Rapid onset of action
• Favorable safety profile when used as directed
• Compliance with veterinary pharmaceutical standards

Usage Guidelines and Safety

Amoxicillin injection 1g should be administered via intramuscular injection. Users must shake the vial well before use to ensure proper suspension. Hypersensitivity reactions, including allergic responses, are possible, and the product should not be used in animals with known beta-lactam allergies.

Important safety precautions:

• Withdrawal periods: 28 days for meat, 4 hours for milk
• Storage: Keep sealed, protected from light, and out of children's reach
• Packaging: 100ml/bottle with a 3-year shelf life

For human milk safety, amoxicillin injection uses must not be used in lactating animals. Milk from treated cattle can only be consumed 96 hours after the last dose.

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a leading manufacturer of veterinary pharmaceuticals, specializing in antibiotics and antimicrobial agents. The company adheres to international quality standards, ensuring its products meet rigorous safety and efficacy requirements.

As a veterinary pharmaceutical company, Shijiazhuang Shimu focuses on developing cost-effective solutions for livestock health. Their commitment to innovation and quality has established them as a trusted supplier in the veterinary industry.

Conclusion

Amoxicillin Injection is a vital tool in veterinary medicine, offering effective treatment for bacterial infections in cattle and pigs. Its pharmacokinetic profile, ease of administration, and safety record make it a preferred choice for livestock producers. For more information, visit the Amoxicillin Injection product page or contact Shijiazhuang Shimu Pharmaceutical Co., Ltd.

References

While no direct references from NIST were found during this research, the technical specifications and safety guidelines for Amoxicillin Injection align with general veterinary pharmaceutical standards. For additional information on antibiotic use in livestock, consult authoritative sources such as the U.S. Food and Drug Administration or the World Organisation for Animal Health.