Amoxicillin Injection-Veterinary Use|Broad-Spectrum Antibiotic

Introduction to Amoxicillin Injection

Amoxicillin Injection is a broad-spectrum antibiotic belonging to the amino-penicillin family, widely used in veterinary medicine for its efficacy against both Gram-positive and Gram-negative bacteria. Derived from ampicillin, this semisynthetic penicillin is renowned for its bactericidal action, which inhibits bacterial cell wall synthesis and reparation. Its applications span across various species, particularly in cattle and pigs, where it targets pathogens like Mannheimia haemolytica and Pasteurella multocida—common culprits in respiratory diseases. For a deeper understanding of its role in veterinary care, visit the product page.

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Product Overview and Composition

Amoxicillin Injection is formulated to deliver precise therapeutic doses, with each milliliter containing 150 mg of amoxicillin. This concentration ensures rapid and effective treatment of bacterial infections. The product is indicated for use in cattle and pigs, addressing infections caused by a wide range of microorganisms. Its time-dependent antibiotic mechanism allows for sustained efficacy, making it a preferred choice for veterinarians. For detailed specifications, explore the product page.

Pharmacokinetic Properties

Understanding the pharmacokinetics of Amoxicillin Injection is crucial for optimizing its therapeutic outcomes. Here’s a breakdown of its behavior in the body:

• Absorption: After intramuscular administration, the drug reaches peak plasma concentration (Cmax) in 2.45 hours for cattle and 2 hours for pigs, with Cmax values of 3.45 µg/ml and 3.54 µg/ml, respectively.
• Distribution: Amoxicillin predominantly resides in the extracellular compartment, aided by its low plasma protein binding (17%). It effectively distributes to pulmonary, pleural, and bronchial tissues, matching plasma concentrations. It also diffuses into pleural, synovial, and lymphatic tissues.
• Metabolism: The liver metabolizes amoxicillin via hydrolysis of the β-lactam ring, forming inactive penicilloic acid (20%).
• Excretion: The majority of the drug is excreted via the kidneys in its active form, with secondary routes including the biliary system and milk.

These properties ensure broad tissue penetration and sustained antibacterial activity, making it ideal for treating respiratory infections in livestock.

Applications and Indications

Amoxicillin Injection is specifically indicated for treating infections caused by Gram-positive and Gram-negative bacteria in cattle and pigs. Its efficacy against Mannheimia haemolytica and Pasteurella multocida positions it as a critical tool in managing respiratory diseases. These pathogens are prevalent in livestock, leading to conditions such as pneumonia and bronchitis. By targeting these bacteria, the injection helps reduce morbidity and mortality in affected animals. For more on its applications, visit the product page.

Advantages of Amoxicillin Injection

Amoxicillin Injection offers several advantages that make it a preferred choice in veterinary medicine:

• Broad-Spectrum Activity: Effective against a wide range of bacteria, reducing the need for multiple antibiotics.
• Fast Onset of Action: Rapid absorption and distribution ensure quick therapeutic effects.
• Good Safety Profile: Minimal side effects when used as directed, with only occasional local reactions at the injection site.
• Convenient Administration: Available in a 100ml bottle, allowing for easy dosing in large animal populations.

These benefits make it an essential component of livestock health management. Learn more about its advantages at the product page.

Product Specifications Table

Company Background: Shijiazhuang Shimu Pharmaceutical Co., Ltd.

Shijiazhuang Shimu Pharmaceutical Co., Ltd. is a reputable manufacturer of veterinary pharmaceuticals, dedicated to producing high-quality antibiotics and medications. With a focus on innovation and compliance with international standards, the company ensures that its products meet rigorous safety and efficacy criteria. Their commitment to animal health is reflected in the development of Amoxicillin Injection, which is designed to address the specific needs of livestock. For more information about the company, visit the product page.

Safety and Precautions

While Amoxicillin Injection is generally safe, certain precautions must be observed:

• Allergies: Avoid use in animals with a known hypersensitivity to β-lactam antibiotics.
• Local Reactions: Transient injection site reactions may occur but are typically mild.
• Withdrawal Periods: Adhere to the 28-day meat withdrawal period and 4-hour milk withdrawal period to ensure consumer safety.
• Storage: Keep the product sealed and protected from light to maintain potency.

For detailed safety guidelines, refer to the product page.

Conclusion

Amoxicillin Injection stands out as a reliable and effective antibiotic for managing bacterial infections in cattle and pigs. Its robust pharmacokinetic profile, broad-spectrum activity, and favorable safety record make it a cornerstone of veterinary care. Manufactured by Shijiazhuang Shimu Pharmaceutical Co., Ltd., the product exemplifies the company’s dedication to animal health and pharmaceutical excellence. As with all medications, adherence to usage guidelines and withdrawal periods is essential to ensure optimal outcomes. For further details, explore the product page.

References

This article incorporates information from the National Institute of Standards and Technology (NIST), which provides critical standards and guidelines for pharmaceutical research and development. While specific data on Amoxicillin Injection is not directly referenced here, NIST’s role in advancing measurement science ensures the reliability of such products. For more on NIST’s contributions to healthcare, visit NIST’s official website.